Convalis (Gabapentin) 300 mg 50 capsules

Convalis (Gabapentin) 300 mg 50 capsules

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Convalis (Gabapentin) Antiepileptic drug, monotherapy for partial seizures
Active substance:Gabapentin
Pharmacological group:Antiepileptic drug
Formulation:Capsules
Dosage mg:300
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Instructions for Convalis (Gabapentin) 300 mg 50 capsules

English product name
Convalis

Release form
Capsules

Description:

Capsules size №0, yellow; The capsule contents are white or yellowish crystalline powder.

1 cap.
Gabapentin 300 mg
Auxiliary substances: lactose monohydrate - 66 mg, corn starch pregelatinized - 30 mg, talc - 3 mg, magnesium stearate - 1 mg.
The composition of the body and cap of the capsule: titanium dioxide (E171) - 2%, iron oxide yellow (E172) - 0.6286%, gelatin - up to 100%.
10 pcs - box-type contour (5) packages - cardboard packs.

ATC codes
N03AX12 Gabapentin

Clinical-pharmacological groups / Group affiliation
Anticonvulsive preparation

Active substance
Gabapentin

Pharmacotherapy group
Antiepileptic agent

Storage Conditions:

The drug should be stored in a dry, protected from light and inaccessible to children at a temperature not higher than 25 ° C.

Best before date
Shelf life is 3 years.

Testimony:

treatment of neuropathic pain in adults 18 years and older (Gabapentin efficacy and safety for neuropathic pain in patients under 18 years of age are not established);
monotherapy of partial seizures with and without secondary generalization in adults and children aged 12 and older (the effectiveness and safety of Gabapentin in monotherapy of partial seizures in children under 12 years of age are not established).

Method of use, course and dosage:

Convalis® is administered inwards regardless of food intake. If it is necessary to reduce the dose, cancel the drug or replace it with an alternative remedy, this should be done gradually for at least one week

Neuropathic pain in adults

The initial dose is 900 mg/day in 3 doses in equal doses; if necessary, depending on the effect, the dose is gradually increased to a maximum of 3,600 mg/day.

Treatment can be started immediately at a dose of 900 mg/day (300 mg 3 times daily) or the dose can be increased gradually to 900 mg/day for the first 3 days as follows:

Day 1: 300 mg of the drug 1 times/day;
Day 2: at 300 mg of the preparation 2 times/day;
Day 3: 3 times/day 300 mg.

Partial convulsions

Epilepsy usually requires long-term treatment. The dose of the drug is determined by the treating doctor depending on the individual tolerability and effectiveness of the drug.

Terms of Sale
The drug is prescription.

Use in children
The use of the preparation is contraindicated in children under the age of 12 years.

Nosology (ICD codes)
B02.2
Shingles with other nervous system complications
G40
Epilepsy
G53.0
Neuralgia after shingles (B02.2)
G63.2
Diabetic polyneuropathy
R52.2
Other persistent pain (chronic)

Pharmacological effect:

The chemical structure of Gabapentin is similar to that of the neurotransmitter GABA, but its mechanism of action differs from other active substances that interact with GABA synapses, such as valproates, barbiturates, benzodiazepines, GABA transaminase inhibitors, GABA reuptake inhibitors, GABA agonists, and GABA prodrugs. In studies of in vitro labeled Gabapentin radioisotope in the brains of rats, new areas of the drug's binding to proteins, including the neocortex and hippocampus, have been found, which may be related to the anticonvulsive and analgesic activity of Gabapentin and its derivatives. Gabapentin has been found to be bound by the α-2-δ (alpha-2-delta) subunit of potential-dependent calcium channels.

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