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Strepsils Intensive

SKU:960
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Pharmacological group:Sore throat remedies
Country of origin:United Kingdom
Expiration Date:Always fresh
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Instructions for Strepsils Intensive

Pharmacological properties:

A symptomatic remedy for the relief of sore throat in infectious and inflammatory diseases of the oral cavity and pharynx. Analgesic and anti-inflammatory activity is due to inhibition of the COX enzyme and inhibition of prostaglandin synthesis. The drug has a local effect. Equally inhibits the action of prostaglandins E 2 and E 2a due to inhibition of endoperoxidase, which catalyzes the conversion of arachidonic acid into cyclic endoperoxide.

The maximum concentration of flurbiprofen in blood plasma is observed 30–40 minutes after the lozenge is absorbed in the oral cavity. The drug is actively metabolized by methylation and hydroxylation, followed by renal elimination. The main metabolites of the drug are 4'oxy-flurbiprofen and 3'-hydroxy-4'methoxy-flurbiprofen. Approximately 70% of the dose is excreted in the urine after 24 hours. The half-life is 3–6 hours.

Indications STREPSILS Intensive:

Symptomatic treatment of sore throat in case of infectious and inflammatory diseases of the mouth and pharynx (viral, bacterial or fungal infections, as well as non-infectious factors that provoke the inflammatory process).

Application:

The lozenges dissolve in the mouth until they are completely dissolved. Adults and children 12 years of age and older take 1 lozenge every 2-3 hours until pain is relieved. The maximum daily dose is 5 lozenges.
Do not use the drug for more than 3 days.
When absorbing, the lozenge should be moved throughout the mouth to prevent irritation of the mucous membrane at the site of absorption.

Contraindications:

Hypersensitivity to any component of the drug; peptic ulcer in the acute phase; BA and rhinitis with the use of acetylsalicylic acid or other NSAIDs; children under the age of 12; period of pregnancy.

Side effects STREPSILS:

They are mainly associated with a distortion of taste and elements of paresthesia in the form of burning, tingling or tingling. Irritation of the oral mucosa is possible. There is a potential, albeit insignificant, risk of developing adverse reactions that are inherent in drugs of the NSAID group from the gastrointestinal tract (nausea, vomiting, exacerbation of gastric ulcer), hematopoietic organs (anemia, thrombocytopenia, leukopenia, agranulocytosis), the nervous system (headache, ataxia, paresthesia, dizziness), urinary system (tubulopathy).

special instructions STREPSILS Intensive:

Use during pregnancy and lactation.
The drug is contraindicated during pregnancy.
The period of breastfeeding is not a contraindication for the use of the drug due to the low concentration of flurbiprofen in breast milk during its use.
The ability to influence the reaction rate when driving or driving other mechanisms.
Dizziness is possible when using the drug. If this side effect manifests itself, then it is not recommended to drive vehicles and other mechanisms.
The drug is used with caution in case of impaired liver and kidney function, hypertension. The drug may prolong bleeding time, which increases the risk of gastrointestinal bleeding.

Interactions STREPSILS Intensive:

With simultaneous use, flurbiprofen can enhance the effect of anticoagulants and weaken the effect of diuretics (furosemide). Flurbiprofen slows down the elimination of lithium. Non-steroidal drugs should be used 8–12 days after taking mifepristone because they can reduce the effectiveness of the latter.

Overdose STREPSILS Intensive:

Symptoms
Nausea, vomiting, dizziness, arterial hypotension, drowsiness, headache, miosis, diplopia.

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