Instructions for Ambene Visco Midi (sodium hyaluronate) 1,5%
Drug properties
Ambene® Visco Midi 1.5% is a synovial fluid prosthesis designed for intra-articular administration. The drug is supplied in the form of full syringes and is used to improve joint mobility, reduce pain, reduce inflammation and restore the homeostasis of cartilage tissue with degenerative changes in its surface.
Ambene® Visco Midi 1.5% is a sterile, viscous solution of sodium salt of hyaluronic acid with a molecular mass of at least 3 MDa. Hyaluronic acid is an important component of the extracellular cartilage matrix and synovial fluid. It gives synovial fluid viscosity and elasticity, which improves the functional condition of the joint.
Intra-articular injection of hyaluronic acid reduces friction of joint surfaces, reduces pain and inflammation, protects the cartilage from premature wear and destruction, improves mobility and absorbs shocks, protecting the components of the joint. Sodium hyaluronate solution is locally distributed in the joint cavity, where it is altered and has a lubricating effect.
The drug cannot be replaced or removed because it is mixed with joint fluid.
Studies of similar drugs suggest that the therapeutic effect may last up to 6 months or longer, depending on the site of administration, degree of disease, and individual characteristics of the body.
Product scope Ambene® Visco Midi:
increased joint mobility and reduced pain in osteoarthritis, osteoarthritis and other degenerative-dystrophic or post-traumatic changes;
rehabilitation after joint surgery and arthroscopy;
support for increased loads on damaged joints.
Recommendations for use sodium hyaluronate
The drug is injected directly into the joint cavity. The method of administration and frequency of procedures are chosen by the doctor individually, based on the degree of degenerative or traumatic changes observed in the joint.
For the knee joint, a single syringe injection once a week is recommended. The course of treatment includes up to three injections, according to the generally accepted methodology described below. In such cases, a 21G needle is used. For other joints, choose the needle that is the appropriate size (17 to 22G) depending on the type of joint.