Instructions for Ampicillin + Sulbactam powder 1 vial + 1 ampoule
English product name
Ampicillin + Sulbactam
Release form
1 g+500 mg injection powder d/p-ra d/v/v and v/m: fl 10 pcs
Description:
Powder for solution preparation for in/in and in/m introduction 1 fl
ampicillin (sodium salt) 1g
sulbactam (sodium salt) 500 mg
Bottles (10) - cardboard packs.
ATC codes
J01CR01 Ampicillin in combination with beta-lactamase inhibitors
Clinical-pharmacological groups / Group affiliation
Broad-spectrum penicillin group antibiotic with beta-lactamase inhibitor
Active substance
- ampicillin (sodium salt)
- sulbactam (sodium salt)
Pharmacotherapy group
Antibiotic, penicillin semisynthetic+beta-lactamase inhibitor
Testimony:
- Treatment of infectious inflammatory diseases caused by sensitive pathogens: respiratory infections (including pneumonia, lung abscess, chronic bronchitis, pleura empiema);
- ENT organ infections (including sinusitis,
- tonsillitis, otitis media);
- urinary tract and genital infections (pyelonephritis,
- pielitis,
- cystitis,
- urethritis,
- prostatitis, endometritis);
- Biliary tract infections (cholecystitis, cholangitis);
- skin and soft tissue infections (rye, impetigo, secondary dermatitis);
- GI infections (dysentery,
- salmonellosis, salmonellosity); bone and joint infections;
- septic endocarditis;
- meningitis;
- sepsis;
- peritonitis;
- scarlatina;
- gonococcal infection.
- Prevention of post-operative complications in abdominal and pelvic organs.
Method of use, course and dosage:
V/m, v/v (drip at a speed of 60-80 kap/min, jet - slowly, for three - five minutes).
The B/C is given five days, and then, if necessary, the treatment is continued, it is given a B/M application.
The following are the total doses of ampicillin and sulbactam (in a ratio of 2:1).
In case of mild infection - 1.5-3 g/day in two injections; For medium-heavy flow - three-six g/day in 3-4 injections; In case of heavy flow - 12 g/day in three or four injections.
For uncomplicated gonorrhea - 1.5 g, once.
For the prevention of surgical infections - 1.5-3 g, during anesthesia; Then for 24 hours after surgery - at the same dose every 6-8 hours.
For children, a daily dose of 150 mg/kg (100 mg/kg ampicillin and 50 mg/kg sulbactam); multiplicity - 3-4 times/day.
For newborns under 1 week old and premature babies every 12 hours.
The course of treatment - 5-14 days (if necessary, can be extended). After the temperature has returned to normal and other pathological symptoms have disappeared, treatment continues for another 48 hours.
For HPN (CC less than 30 ml/min) it is necessary to increase the intervals between injections.
Use in liver disorders
Cautious: liver failure.
Use in children
Application is possible according to dosing regime.
- Nosology (ICD codes)
- A02
- Other salmonella infections
- A03
- Shigellosis
- A09
- Other gastroenteritis and colitis of infectious and unspecified origin
- A38
- Scarlatina
- A40
- Streptococcal sepsis
- A41
- Other sepsis
- A46
- Rozha
- A54
- Gonococcal infection
- G00
- Bacterial meningitis not classified elsewhere
- H66
- Pus and unspecified mean otitis
- I33
- Acute and subacute endocarditis
- D01
- Acute sinusitis
- D02
- Acute pharyngitis
- D03
- Acute tonsillitis
- J04
- Acute laryngitis and tracheitis
- D15
- Bacterial pneumonia not classified elsewhere
- J20
- Acute bronchitis
- J31.2
- Chronic pharyngitis
- J32
- Chronic sinusitis
- J37
- Chronic laryngitis and laryngotracheitis
- J42
- Chronic bronchitis unspecified
- J85
- Abscess of the lung and mediastinum
- J86
- Piothorax (Pleura Empirical)
- K65.0
- Acute peritonitis (including abscess)
- K81.0
- Acute cholecystitis
- K81.1
- Chronic cholecystitis
- K83.0
- Holangite
- L01
- Impetigo
- L02
- Skin abscess, boils and carbuncles
- L03
- Phlegmona
- L08.0
- Piodermia
- L08.8
- Other refined local skin and subcutaneous tissue infections
- L30.3
- Infectious dermatitis (infectious eczema)
- M00
- Piogenic arthritis
- M86
- Osteomyelitis
- N10
- Acute tubuloinsterstitial nephritis (acute pielonephritis)
- N11
- Chronic tubulointerstitial nephritis (chronic pyelonephritis)
- N30
- Clean
- N34
- Urethritis and urethral syndrome
- N37.0
- Urethritis in diseases classified in other headings
- N41
- Inflammatory prostate diseases
- N70
- Salpingitis and oophorite
- N71
- Inflammatory disease of the uterus, except the cervix (including endometritis, myometritis, metritol, pyometra, abscess of the uterus)
- N72
- Inflammatory disease of the cervix (incl. cervicite, endocervicite, exocervicite)
- N73.5
- Pelvic peritonitis in women unspecified
- N74.3
- Gonococcal inflammatory diseases of the female pelvic organs
- T79.3
- Post-traumatic wound infection not classified elsewhere
- Z22.1
- Carrier of pathogens of other gastrointestinal infectious diseases
- Z29.2
- Another type of preventive chemotherapy (antibiotic administration for preventive purposes
Pharmacological effect:
A broad-spectrum combined antibacterial agent.
Ampicillin is an antibiotic of the semi-synthetic penicillin group, the bactericidal action of which is connected with suppression of synthesis of proteins of the cell wall of microorganisms.
