indications for Antigrippin-Anvi
Structure Antigrippin-Anvi:
1 capsule A contains Antigrippin-Anvi: Active ingredients: acetylsalicylic acid - 250 mg, ascorbic acid - 300 mg, rutoside - 20 mg.
Capsules of two types:
1 green capsule contains:
Active ingredients Antigrippin-Anvi:
Acetylsalicylic acid 250 mg.
Acorbic acid 300 mg.
Rutin 20 mg.
Excipients: calcium stearate - 1 mg, potato starch - 9 mg.
Composition of hard gelatin capsules: gelatin - 90.723 mg, azorubin dye (E122) - 0.003 mg, diamond black dye (E151) - 0.184 mg, patent blue dye (E131) or brilliant blue dye (E133) - 0.315 mg, quinoline yellow dye ( E104) - 2.207 mg, titanium dioxide (E171) - 2.56 mg.
1 white capsule contains Antigrippin-Anvi:
Active ingredients
Metamizole 250 mg.
Diphenhydramine 20 mg.
Calcium gluconate 100 mg.
Excipients: calcium stearate - 3.8 mg, potato starch - 6.2 mg.
Composition of hard gelatin capsules: gelatin - 91.944 mg, titanium dioxide (E171) - 4.055 mg.
Pharmaco-therapeutic group Antigrippin-Anvi
ARI and cold symptoms are remedies.
Pharmacological properties Antigrippin-Anvi:
The drug Antigrippin-Anvi is a combined composition.
Acetylsalicylic acid has analgesic, antipyretic and anti-inflammatory effects; inhibits platelet aggregation.
Ascorbic acid plays an important role in the regulation of redox processes, carbohydrate metabolism, blood clotting, tissue regeneration, and helps to increase the body's resistance.
Rutoside (rutin) is an angioprotective agent. Reduces capillary permeability, reduces swelling and inflammation, strengthens the vascular wall. It inhibits aggregation and increases the degree of erythrocyte deformation.
Metamizole sodium has an analgesic, antipyretic and weak anti-inflammatory effect, the mechanism of which is associated with inhibition of prostaglandin synthesis.
Diphenhydramine has antiallergic, anti-edema effect. Reduces vascular permeability, eliminates swelling and hyperemia of the nasal mucosa, sore throat and manifestations of allergic reactions from the upper respiratory tract.
Calcium gluconate is a regulator of calcium and phosphorus metabolism, has antiallergic effect (the mechanism is unclear), and reduces vascular permeability. For allergic diseases or conditions, it is recommended to use it together with antihistamines. Antigrippin-Anvi
Overdose Antigrippin-Anvi
Symptoms: nausea, vomiting, stomach pain, sweating, pallor of the skin, tachycardia; with a slight overdose - ringing in the ears; with severe overdose - drowsiness, collapse, convulsions, bronchospasm, shortness of breath, anuria, bleeding, progressive respiratory paralysis and respiratory acidosis (due to uncoupling of oxidative phosphorylation).
Antigrippin-Anvi Treatment: artificial vomiting, gastric lavage, the appointment of saline laxatives, activated carbon; with the development of convulsive syndrome - intravenous administration of diazepam and barbiturates; if necessary - carrying out forced diuresis, hemodialysis.
Indications for use Antigrippin-Anvi
Symptomatic treatment of influenza, ARVI, colds in adults and adolescents over 15 years old.
Mode of application Antigrippin-Anvi
The drug Antigrippin-Anvi is prescribed internally for adults and adolescents over 15 years of age, 2 capsules per dose: 1 green capsule (from blister A) and 1 white capsule (from blister B).
The duration of admission is 3-5 days until the symptoms of the disease disappear.
Capsules are taken orally 2-3 times / day after meals with water. The patient should be warned that if there is no improvement in health, the drug should be discontinued and consult a doctor.
Contraindications Antigrippin-Anvi:
Erosive and ulcerative lesions of the gastrointestinal tract (in the acute phase).
Gastrointestinal bleeding.
Increased bleeding tendency.
Bronchial asthma and diseases accompanied by bronchospasm (including "aspirin" asthma).
Inhibition of hematopoiesis (agranulocytosis, neutropenia, leukopenia).
Hemorrhagic diathesis (hemophilia, von Willebrand disease, telangiectasia, hypoprothrombinemia, thrombocytopenia, thrombocytopenic purpura).
Severe liver dysfunction.
Portal hypertension.
Severe renal failure.
Hereditary hemolytic anemia (including those associated with a deficiency of glucose-6-phosphate dehydrogenase).
Aortic dissecting aneurysm.
Hypercalcemia (the concentration of calcium ions should not exceed 12 mg% or 6 meq / l).
Hypercalciuria.
Nephrolithiasis (calcium).
Sarcoidosis
Glycosidic intoxication (risk of arrhythmia).
Pregnancy.
Lactation period (breastfeeding).
Children and adolescents up to 15 years old.
Hypersensitivity to drug components.
With caution: the drug is prescribed for hyperuricemia, urate nephrolithiasis, gout, gastric and duodenal ulcers (in history), decompensated heart failure.
Side effects Antigrippin-Anvi:
From the digestive system: anorexia, nausea, vomiting, gastralgia, diarrhea, erosive and ulcerative lesions of the gastrointestinal tract, gastrointestinal bleeding, liver failure.
From the urinary system: renal failure.
Allergic reactions: skin rash, Quincke's edema, bronchospasm.
Side effects are observed with prolonged use of the drug (more than 7 days).
From the side of the central nervous system: dizziness, headache. Antigrippin-Anvi
From the senses: visual impairment, tinnitus, deafness, hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis.
From the side of the blood coagulation system: decreased platelet aggregation, hypocoagulation, hemorrhagic syndrome (including nosebleeds, bleeding gums, purpura).
special instructions Antigrippin-Anvi
The drug Antigrippin-Anvi is not prescribed as an antipyretic agent for children under 15 years of age with acute respiratory viral diseases due to the risk of developing Reye's syndrome (encephalopathy and acute fatty degeneration of the liver with acute development of liver failure).
With prolonged use of the drug, it is necessary to monitor the picture of peripheral blood and laboratory parameters of the functional state of the liver.
Since acetylsalicylic acid has an antiplatelet effect, the patient, if he is to undergo surgery, must warn the doctor in advance about taking the drug.
Acetylsalicylic acid in low doses reduces the excretion of uric acid, which can, in some cases, provoke an attack of gout.
While using the drug, patients should avoid drinking alcoholic beverages due to the increased risk of gastrointestinal bleeding.
Acetylsalicylic acid has a teratogenic effect: when used in the first trimester of pregnancy, it leads to the development of cleavage of the upper palate; in the third trimester - to the premature closure of the ductus arteriosus in the fetus, which causes hyperplasia of the pulmonary vessels and hypertension in the vessels of the pulmonary circulation, and to inhibition of labor (due to inhibition of prostaglandin synthesis).
Acetylsalicylic acid is excreted in breast milk, which increases the risk of bleeding in a child due to dysfunction of platelets. Antigrippin-Anvi
In connection with the stimulating effect of ascorbic acid on the synthesis of corticosteroid hormones, it is necessary to monitor renal function and blood pressure.
The administration of ascorbic acid to patients with rapidly proliferating and intensely metastatic tumors can aggravate the process.
Ascorbic acid, as a reducing agent, can distort the results of various laboratory tests (determination of glucose, bilirubin and the activity of "hepatic" transaminases, LDH in blood plasma). Antigrippin-Anvi
In patients with bronchial asthma and hay fever, hypersensitivity reactions may develop when taking the drug.
Influence on the ability to drive vehicles and use mechanisms Antigrippin-Anvi
During the period of drug use, one should refrain from engaging in potentially hazardous activities that require increased attention and speed of psychomotor reactions.