Instructions for BIOFER (Iron III hydroxide polymaltozate, folic acid)
Latin name:
BIOFER
Product form chewable:
tablets
International Classification of Diseases (ICD-10):
D50
Iron deficiency anemia
E61.1
Iron deficiency
O99. 0
Indications:
Anemia that complicates pregnancy, childbirth and the postpartum period
Pharmacological Group:
Antianemic drug
Pharmacological action:
Antianemic drug. The preparation Biofer contains iron in the form of a polymaltose complex of iron (III) hydroxide. This macromolecular complex is stable and does not release iron in the form of free ions in the gastrointestinal tract. The structure of the Biofer is similar to the natural iron compound ferritin. Due to this similarity, iron (III) is supplied from the intestine to the blood by active transport. It is this property that explains the impossibility of overdosing the drug in contrast to simple iron salts, the absorption of which occurs along a concentration gradient.
The absorbed iron binds to ferritin and is stored in the body, mainly in the liver. Then, in the bone marrow, it is included in the composition of hemoglobin. Iron, which is part of the polymaltose complex of iron (III) hydroxide, does not have pro-oxidant properties, unlike simple iron salts. There is a correlation between the severity of iron deficiency and the level of its absorption (the greater the severity of iron deficiency, the better the absorption). The most active process of absorption occurs in the duodenum and small intestine.
Folic acid is a B vitamin that stimulates erythropoiesis, participates in the synthesis of amino acids, nucleic acids, purines, pyrimidines, and choline metabolism.
Taking the drug Biofer in the dosage form of chewable tablets does not cause staining of the enamel of the teeth.
Pharmacokinetics:
Data on the pharmacokinetics of the drug Biofer are not provided.