Candiderm cream

Instructions for Candiderm

Release form Candiderm cream:

Description Candiderm cream

Cream for external use, white, homogeneous: 1 g
clotrimazole: 10 mg
beclomethasone dipropionate: 0.25 mg
gentamicin (as gentamicin sulfate): 1 mg
propylene glycol, cetomacrogol, petrolatum, liquid paraffin, benzyl alcohol, methyl parahydroxybenzoate (methylparaben), propyl parahydroxybenzoate (propylparaben), butylhydroxytoluene, sodium dihydrogen phosphate monohydrate water, purified sodium hydrogen phosphate

(Beclomethasone in combination with antibiotics)

pharmacological Candiderm cream:

Drug with antibacterial, antifungal and anti-inflammatory action for external use

Active substance Candiderm cream:

• clotrimazole
• gentamicin
• beclomethasone dipropionate

Pharmaco-therapeutic group Candiderm cream:

Glucocorticosteroid/antibiotic aminoglycoside/antifungal agent

Storage conditions Candiderm cream:

The drug should be stored out of the reach of children, protected from light at a temperature not exceeding 25 ° C; do not freeze.

pharmachologic effect Candiderm cream:

Combined preparation for external use with anti-inflammatory, anti-allergic, antifungal and antibacterial action.
Clotrimazole has an antifungal effect by disrupting the synthesis of ergosterol, which is an integral part of the fungal cell membrane. Active against Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis, Candida albicans, Malassezia furfur (Pityrosporum orbiculare).

Beclomethasone has anti-inflammatory, anti-allergic, anti-exudative and antipruritic effects. It inhibits the accumulation of leukocytes, the release of lysosomal enzymes and inflammatory mediators, inhibits phagocytosis, reduces vascular tissue permeability, and prevents the formation of inflammatory edema.

Gentamicin is a broad-spectrum antibiotic from the aminoglycoside group that has a bactericidal effect against gram-negative bacteria: Pseudomonas aeruginosa, Enterobacter aerogenes, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae; gram-positive bacteria: Streptococcus spp., Staphylococcus aureus.

Indications Candiderm cream:

dermatoses complicated by secondary infection
athlete's foot
dermatomycosis (including with localization in the groin area) caused by pathogens sensitive to the drug

Method of application Candiderm cream:

The drug is used externally. The cream is applied in a thin layer to the affected skin 2 times / day (morning and evening). The duration of treatment depends on the effectiveness and tolerability of therapy and is usually no more than 2-4 weeks.
In children aged 7-16 years, the drug is used strictly according to indications and under medical supervision.

Overdose Candiderm cream:

Symptoms: weight gain, edema, arterial hypertension, glucosuria, hypokalemia (symptoms of hypercortisolism).
Treatment: symptomatic therapy, if necessary, correction of the electrolyte balance. A gradual withdrawal of the drug is recommended.

Drug interactions Candiderm:

The interaction of the drug with other drugs has not been identified.

Application during pregnancy and lactation Candiderm cream
Use during pregnancy and during breastfeeding is contraindicated.

Side effect Candiderm:

Dermatological reactions: burning sensation, hyperemia, erythema, peeling, dryness, maceration, skin atrophy, striae, hypertrichosis, folliculitis, prickly heat, steroid acne, perioral dermatitis, telangiectasia, hypopigmentation, pyoderma, furunculosis.

Allergic reactions: edema, urticaria, allergic contact dermatitis.
Systemic reactions (including suppression of the function of the adrenal cortex) are possible with prolonged use.

Indications Candiderm:

• Mycosis
• Dermatoses complicated by secondary infection
• athlete's foot
• Epidermophytosis inguinal
• Candidiasis of the skin and nails
• Infectious dermatitis (infectious eczema)

Contraindications Candiderm:

• lupus
• cutaneous manifestations of syphilis
• chickenpox
• herpes simplex
• post-vaccination skin reactions
• open wounds
• children under 7 years of age
• pregnancy
• lactation period (breastfeeding)
• hypersensitivity to drug components
• The drug is not used in ophthalmology.

special instructions Candiderm:

It is contraindicated to apply to the skin in the eye area.
In order to increase the effectiveness of therapy, it is possible to use occlusive dressings. It should be borne in mind that this increases the transdermal absorption of beclomethasone and gentamicin, which leads to an increased risk of systemic side effects.

If persistent bacterial or fungal microflora appears, the drug should be discontinued and appropriate therapy should be prescribed.
Development of cross-resistance with aminoglycoside antibiotics is possible.
Use in pediatrics

For children, the drug is prescribed only on strict indications and under medical supervision. possible systemic side effects associated with beclomethasone. When using the drug on large surfaces and / or under an occlusive dressing, it is possible to suppress the function of the hypothalamic-pituitary-adrenal system and develop symptoms of hypercortisolism; there may also be a decrease in the excretion of growth hormone and an increase in intracranial pressure.

Application in children Candiderm
It is contraindicated for use in children under 7 years of age.
In children aged 7-16 years, the drug is used strictly according to indications and under medical supervision.