Instructions for Cerebroforce (choline alfoscerate) 5 ampoules
Indications Cerebroforce
Cerebrovascular disorders of the ischemic type (acute and recovery periods) and hemorrhagic type (recovery period), psychoorganic syndrome during involutional and degenerative processes in the brain.
Cognitive impairment in older people:
Cerebrovascular insufficiency: Primary and secondary impairments characterized by memory impairment, confusion, confusion, and decreased motivation, initiative, and concentration.
Multi-infarct dementia: A condition caused by multiple minor strokes that gradually reduces cognitive function.
Emotional and behavioral changes in old age:
Emotional lability: Increased tendency to sudden mood swings.
Irritability: increased sensitivity to external stimuli, a tendency to conflict.
Decreased interest in others: Decreased involvement in daily activities and social interactions.
Senile pseudomelancholy: A condition in which older people may show symptoms of depression, such as sadness, loss of interest in life, and feelings of hopelessness, but without the profound depression that occurs in younger people.
Packaging and form of issue
The solution for intravenous and intramuscular injections, containing 250 mg/ml of active substance, is available in ampoules of four ml. The package contains 5 vials.
Pharmacotherapeutic group Cerebroforce
Nootropic agent.
Mode of application and dose
The drug is administered intravenously by droplets or intramuscularly slowly at a daily dose of 1000 mg.
For IV administration, the contents of one vial (4 mL) are dissolved in 50 mL of 0.9% saline solution and infused at a rate of 60 to 80 drops per minute.
Treatment usually takes 10 days.
Pharmacodynamics
Choline alfoscerate is a central-acting cholinomytic drug that primarily affects the central nervous system.
It contains 40.5% choline, which is released in the brain. Choline is involved in the synthesis of acetylcholine, a key neurotransmitter. Alphospherate is converted to glycerophosphate, which is the precursor of phospholipids.
Acetylcholine improves nerve impulse transmission, and glycerophosphate promotes phosphatidylcholine, an important membrane phospholipid. This increases the elasticity of cell membranes and improves the function of receptors.
Choline alfoscerate activates metabolic processes and stimulates the activity of the reticular formation of the brain.
