Instructions for Ciprolet A (ciprofloxacin, tinidazole) 600 mg + 500 mg
Release Form
Film coated tablets
Description Ciprolet A
The tablets are oval in shape and have a white or almost white film coating. There is a risk dividing line on one side, and a smooth line on the other. A transverse section shows a white or pale yellow kernel.
Indications for use Ciprolet A
- The drug Ciprolet® A is intended for the treatment of mixed bacterial infections caused by tinidazole and ciprofloxacin-sensitive microorganisms, including gram-positive and
- gram-negative aerobic, anaerobic bacteria and protozoa. It is effective in the following conditions:
- Lower respiratory tract diseases, including pneumonia.
- Skin and soft tissue infections.
- Bone and joint disorders.
- Infections of the pelvic organs and genital organs.
- Kidney diseases and complicated urinary tract infections.
- Complicated intra-abdominal infections.
- Cyprolet® A can be used as an alternative to other antimicrobial drugs in the treatment of uncomplicated urinary tract infections. However, before starting therapy, it is necessary to familiarize yourself with current official recommendations for the use of antibacterial agents.
Pharmacotherapeutic group tinidazole
Combined antimicrobial agent from the fluoroquinolone group.
Pharmacological effect Ciprolet A
The preparation combines the properties of the components contained therein.
Ciprofloxacin is a broad-spectrum, fluoroquinolone antimicrobial. It inhibits the bacterial DNA gyrase, which is responsible for the superhelization of chromosomal DNA. This is necessary to read genetic information. Ciprofloxacin interferes with DNA synthesis, inhibits bacterial growth and division, causing significant morphological changes in bacterial cell walls and membranes, leading to rapid death of microorganisms.
The drug acts bactericidally on gram-negative bacteria both at rest and during division, as it affects not only the bacterial DNA gyrase, but also leads to the lysis of the cell wall. Ciprofloxacin has a bactericidal effect on gram-positive bacteria only during the time they are dividing. The low toxicity of the drug to human cells is due to the lack of DNA gyrase in them.
Ciprofloxacin use does not appear to be resistant to other antimicrobial that are not gyrase inhibitors. This makes it effective against bacteria resistant to aminoglycosides, penicillins, cephalosporins, tetracyclines, and other antimicrobial.
Mode of application, course and dosage tinidazole
The drug is given by mouth, one hour before meals or two hours after meals. The recommended dose is one tablet twice a day for 5-10 days.
People should take the pills by drinking enough water. The pill should not be broken, chewed, or destroyed.