Instructions for Clenzit (adapalene) gel 0.1%
Release Form
Gel for external use
ATC codes adapalene
D10AX30 is a code for other combination drugs that are designed to be used externally to treat acne.
Pharmacotherapeutic groups / Pharmacological action
This drug has antibacterial and comedolytic properties, which allows you to effectively fight acne.
Pharmacotherapeutic group Clenzit
Acne treatment.
Storage conditions
The drug should be stored away from children and away from direct sunlight. The storage temperature shall be between 2°C and 25°C.
Shelf life Clenzit
Shelf life is two years. After the expiration of the specified period, the drug is forbidden to use.
Pharmacological effect adapalene
Clenzite-C is a topical combination drug containing microspheres with adapalen and clindamycin. Adapalene is a retinoid metabolite that has an anti-inflammatory effect and a pronounced ability to dissolve comedones (both open and closed). It also normalizes keratinization and differentiation of epidermis.
The mechanism of action of adapalene is based on interaction with γ receptors of skin cells. This leads to a reduction in the adhesion of the epidermal cells to the hair follicle mouth and an acceleration of their exfoliation. As a result, microcomedones are less likely to form.
Adapalene has an anti-inflammatory effect of both in vivo and in vitro. It acts on inflammatory factors by inhibiting white blood cell migration to the site of inflammation and arachidonic acid metabolism. The drug also inhibits chemotaxis and chemokinetic reactions of polynuclear cells, which helps reduce inflammation.
Indications Clenzit
Acne.
Mode of application, course and dosage Clenzit
Clenzit gel with microspheres is intended for external use. Before application, thoroughly clean and dry the skin. With gentle movements, evenly distribute the gel on the affected areas, avoiding contact with the eyes, lips and mucous membranes. It is recommended to use once a day, preferably before bedtime.
Therapeutic effect occurs within one to four weeks. A full course of treatment lasts four to six weeks. Repeated treatment is possible only after consultation with a doctor.
If skin irritation develops, the gel should be stopped until symptoms disappear.
- Nosology (ICD codes)
- L70
- Acne
