Detravenol (Diosmin) [Phlebodia 600]

Instructions for Detravenol (Diosmin) [Phlebodia 600]

Release Form

tab., film cover, 500 mg: 30 or 60 pcs.
tab., film cover, 1000 mg: 30 or 60 pcs.
Description
Pills covered with film wrapped from pink to pale pink, oval, double-bulb, with a risk on one side; Two layers are visible on the cross section: The kernel - from gray-brown to gray-yellow color, with a lighter and darker tint, and a film shell.

1 tab
500 mg purified micronized flavonoid fraction,
including diosmin 450 mg (90%)
Fluvonoids per Hesperidine of 50 mg (10%)
Auxiliary substances: Gelatin - 13.5 mg, sodium carboxymethyl starchmal - 27 mg, Stearat magnesium - 6.5 mg, microcrystalline cellulose - up to 650 mg.

Composition of the membrane:
Opadra II 85F240012 Pink - 20 mg (polyvinyl alcohol - 8 mg, macrogol 3350 - 4.876 mg, iron dye oxide red - 0.08 mg, red iron oxide yellow - 0.044 mg, talc - 2.96 mg, titanium dioxide - 4.04 mg).

10 pcs. - cell contour (3) packaging - cardboard packs.
10 pcs. - cell contour (6) packaging - cardboard packs.

ATX codes
C05CA53 Diosmin in combination with other drugs

Pharmacological groups / Group membership:

Ventonizing and venotrektor drug

Active substance [Phlebodia 600]:

purified micronized flavonoid fraction

Pharmacy Group Detravenol:

Ventonizing and venotrektor

Retention Terms
The drug should be stored in a place not accessible to children at a temperature not exceeding 25°C.

Shelf life
Shelf life - 3 years. Do not apply after expiration date.

Pharmaceuticals Detravenol:

The drug is a purified micronized flavonoid fraction consisting of diosmina and other flavonoids in terms of hesperidine. This combination has venotonizing and angioprotector properties. Reduces the tensile strength of veins and venous stagnation, in microcirculation - reduces the permeability of capillaries and increases their resistance, improves the indicators of venous hemodynamics. Affects the following venous brainwashing parameters: venous capacity, venous stretch, venous discharge time.

The optimal effect is achieved at 1000 mg.

The drug Detravenol increases the venous tone by reducing the time of venous discharge. Patients with signs of microcirculation disturbance are experiencing increased capillary resistance.
The effectiveness of the drug in terms of venous hemodynamics indicators in the treatment of chronic diseases of the veins of the lower limbs, as well as in the treatment of hemorrhoids was demonstrated.

Testimonials Detravenol [Phlebodia 600]:

• Therapy of symptoms of chronic veins (elimination and relief of symptoms);
• Venosno-lymphatic deficiency symptoms therapy:
• pain;
• lower limb cramps;
• a sense of gravity and slack in the legs;
• "fatigue" of the legs.
• therapy of venous-lymphatic insufficiency:
• The edema of the lower limbs;
• trophic changes in skin and subcutaneous fiber;
• venous trophic ulcers.
• Acute and chronic hemorrhoids symptomatic therapy.

Method of application, course and dosage [Phlebodia 600]:

The drug is taken inside. Pills should be swallowed by drinking water. For ease of swallowing, it is possible to divide the pill by risk.

Recommended dose for venous lymphatic insufficiency - 2 tab. per 500 mg or 1 tab. per 1000 mg, preferably in the morning, during meals. The duration of the course of treatment may be several months (up to 12 months). In case of repeated symptoms, the treatment may be repeated on the recommendation of the doctor.

The recommended dose for acute hemorrhoids is 6 tab. per 500 mg per day (2 tab. in the morning, afternoon and evening) or 3 tab. per 1000 mg per day (1 tab. in the morning, afternoon and evening) for 4 days, followed by 4 tab. 500 mg per day (2 tab. in the morning and evening) or 2 tab. per 1000 mg per day (1 tab. in the morning and in the evening) for the following 3 days.
The recommended dose for chronic hemorrhoids is 2 tab. per 500 mg or 1 tab. per 1000 mg per day.

Overdose Detravenol:

No overdoses were reported.
If the drug Detravenol is overdose, the patient should immediately seek medical treatment.

Drug Interaction:

To date, no cases of drug interaction have been reported.
Use in pregnancy and breastfeeding

Pregnancy
Experiments on animals have not revealed teratogenic effects.
So far, there have been no reports of unwanted effects when pregnant women use the drug.

Breastfeeding period
In the absence of data on the injection of breast milk, breast-feeding women are not recommended to use the drug Detravenol.
Influence on reproductive function
Reproductive toxicity studies showed no influence on reproductive function in rats of both sexes.

Special Instructions:

Before taking Detrevanol, it is recommended that the patient consult a doctor.
In the case of hemorrhoids, the use of Detravenol does not replace the specific treatment of other anal disorders.
The duration of treatment shall not exceed the time specified in the section "Dosing mode". In case the symptoms do not disappear after the recommended course of therapy, check with the proctologist who will pick up the further therapy.
If there are vector circulation disorders, the maximum effect of treatment is ensured by combining therapy with a healthy (balanced) lifestyle: It is desirable to avoid long stay in the sun, long stay on the legs, and also recommended to reduce excess body weight. Walking and, in some cases, wearing special stocking helps to improve blood circulation.

If there is no reduction or if the symptoms of the disease become more severe, the patient should consult a doctor.
Patient should be informed that the maximum duration and recommended doses should not be exceeded without the approval of the doctor.
Impact on the ability to drive vehicles and mechanisms
The drug Detravenol does not affect the ability to drive vehicles and mechanisms.

Terms of implementation:

The drug is released without prescription.

Nozology (ICD codes)
I83.2
Variocotherapy extension of the lower limb veins with ulcer and inflammation
I87.2
Venture Insufficiency (Chronic) (peripheral)
Hemorrhoids and perianal venous trombosis
Outlet not classified in other headings