Instructions for Estrogel (Estradiol) Transdermal gel 80 gr
English product name
Estrogel®
Release form
gel transdermal 600 ug/g: fl 80 g with metering pump
gel transdermal 600 ug/g: tuba 80 g with applicator-dosator
Description:
Transdermal gel colorless, transparent, with the smell of ethanol.
1g 1 dose (2.5 g gel)
estradiol (in the form of hemihydrate) 600μg 1.5 mg
Auxiliary substances:
carbomer (carbopol 980) - 5 mg,
trolamine (triethanolamine) - 5 mg,
ethanol - 400 mg, water purified - q.s. up to 1 g.
80 g - plastic bottles (1) with metering pump - packs of cardboard.
ATC codes
G03CA03 Estradiol
Clinical-pharmacological groups / Group affiliation
Anti-climacteric estrogen preparation
Active substance
Estradiol(in the form of hemihydrate)
Pharmacotherapy group
Estrogen
Storage Conditions
The drug should be stored in a place inaccessible to children at a temperature not higher than 25 ° C.
Best before date
Shelf life is 3 years. Do not apply after the expiry date indicated on the package.
Dosage, Course and Dosage Estrogel:
Estrogel® is prescribed externally, continuously or in a cyclic mode. Doses and duration of therapy are set individually.
Usually the initial dose of the drug Estrogel is 2.5 g of gel once a day, which corresponds to 1.5 mg of Estradiol. In most patients, this dose is effective in relieving menopausal symptoms. If, after one month of therapy, the effectiveness is not achieved, it is possible to increase the daily dose of the drug to a maximum of five g of gel, which corresponds to three mg of Estradiol.
To begin and continue the treatment of menopausal symptoms, the minimum effective dose should be used for a minimum period of time.
Testimony:
- hormone replacement therapy for symptoms of estrogen deficiency, treatment of menopausal syndrome associated with
- natural or surgical menopause;
- prevention of osteoporosis in the postmenopausal period in women with a high risk of fractures with intolerance or the
- presence of contraindications to the use of other drugs for the prevention of osteoporosis.
Method of use Estrogel:
The gel is applied by patients independently, in the morning or in the evening, with a thin layer on the clean, dry skin of the abdomen, lumbar area, shoulders or forearms until completely suction. The area of application should be at least 2 palms.
Do not massage the place of application of the gel. It is necessary to avoid getting the gel on the breast and mucosa of the vulva and vagina.
The application is considered correct and effective if the gel is sucked completely within two - three minutes
If the sticky consistency persists for more than five minutes after application, it means the gel is covered with too small skin surface.
The drug Estrozel® does not leave stains.
Wash your hands immediately after applying the gel.
Application of the drug Estradiol in tuba. The tube should be opened and the metal membrane of the tube should be pierced with the help of a small penetrator, which is located in the upper part of the tube lid. The required dose is extracted from the tube according to the applicator line.
one dose corresponds to a column of extracted gel with a diameter corresponding to the diameter of the outlet opening of the tube, the length of which corresponds to the depression on the applicator line. The recess has a line that allows you to divide the daily dose in half. One tube with gel is designed for 30 doses.
The use of the drug Estrogel in a vial. Remove the cap from the bottle and push the dispenser pump hard, exposing the other hand to gel collection. The dose that is released at the first press may not be accurate. It is recommended to throw it away. The bottle is designed for 64 presses. After 64 taps, the amount of gel that is released at one press may be less than necessary. Therefore, it is not recommended to use the bottle after 64 clicks on the metering pump.
Terms of implementation Estrogel
The drug Estrogel is dispensed by prescription.
Use in elderly patients
The experience of treating women over 65 years of age is limited.
- Nosology Estrogel (ICD codes)
- M80.0
- Postmenopausal osteoporosis with pathological fracture
- M80.1
- Osteoporosis with pathological fracture after removal of the ovaries
- M81.0
- Postmenopausal osteoporosis
- M81.1
- Osteoporosis after ovarian removal
- N95.1
- Menopause and menopause in women
- N95.3
- Conditions associated with artificially induced menopause