Instructions for Fastum Gel (Ketoprofen)
Pharmacological properties:
Pharmakodinamika
The fastum gel contains ketoprofen as an active substance, which promotes rapid reduction of superficial inflammatory processes of joints, tendons, ligaments and muscles. Thanks to the use of a special gel base, the deep penetration of the active substance into the skin and soft tissues is ensured without the development of systemic side effects. Fastum gel does not cause addictive phenomena.
Pharmacokinetics:
Absorption of the drug from the surface of the skin and its entry into the systemic bloodstream is slow. When applied to the skin in a dose of 50-150 mg ketoprofen, the concentration of the active substance in blood plasma reaches only 0.08-0.15 μg/ml after 5-8 hours.
Indications:
- Topical use in muscular or bone-joint pain of rheumatic or traumatic origin:
- bruises
- dislocations
- traumatic sprains
- cranks
- back pain (lumbago).
Application:
Used in adults and children over the age of 12 years. The gel is applied in a thin layer onto the affected area 1-2 times a day, squeezing 3-5 cm gel or more out of the tube depending on the size of the painful area, and carefully rubbed it until it is fully absorbed. The drug is used, as a rule, no more than 10 days.
Contraindications:
Increased sensitivity to the preparation, any component thereof or other substances similar in chemical composition.
Side effects:
There are reports of localized skin reactions occurring outside the skin area on which the drug is applied; in some cases, they can take on a severe and generalized character and manifest as erythema, burning, itching, allergic skin rash, dermatitis, contact eczema, light-sensitive reactions, urticaria, the formation of purulent and blisters. Isolated cases of systemic reactions have been reported, for example, impaired kidney function.
Special instructions:
Prolonged use of topical drugs can cause symptoms of hypersensitivity or local irritation. It is not recommended to apply the drug to an open wound and a damaged area of the skin. To prevent the appearance of hypersensitivity or photosensitization reactions, patients are not advised to be exposed to direct sunlight or visit the solarium during treatment and for 2 weeks after the end of the drug.
During pregnancy and breastfeeding, the drug should be prescribed only in case of acute need and used under the supervision of a doctor. It is recommended to regularly monitor the condition of patients receiving a course of treatment with coumarin drugs.
The drug does not affect the ability to drive vehicles or service mechanisms.
Interactions:
Not known
Overdose:
Because the blood plasma ketoprofen level is low, overdose can be ruled out.
Storage conditions:
At temperature not higher than 25 ° С.
