Instructions for Lioton (Heparin Sodium) gel
Pharmaceutical properties
Sodium heparin drug Lioton for local use. Sodium heparin, a direct-action anticoagulant, blocks trombin biosynthesis, prevents the formation of fibrin from fibrinogen, reduces the aggregation of platelets, inhibits the activity of the hyaluronidase and has a moderate effect anti-inflammatory and anti-exudative action.
Lioton 1000 does not cause changes in blood viscosity, does not affect the content of the main folding factors and the level of lipids in the blood.
A small amount of the drug Lioton is resorbated from the skin surface and is discharged into the system blood flow. The maximum concentration in the blood is noted after 8 hours after the drug is applied, is removed from the plasma of the blood within 12-24 hours. It is produced mainly with urine.
- Testimonials:
- Varicose veins and related complications —
- flabotrombosis,
- thrombophlebit,
- surface periflebit,
- varicose ulcers;
- postoperative varicose flabite
- complications after a subcutaneous leg vein removal operation;
- injuries to the musculoskeletal system and soft tissues:
- bruises,
- infiltration and localized swelling,
- subcutaneous hematoms, muscle damage,
- tendons,
- joints.
Application:
Adults in the skin of the affected area are rubbed by a pole of gel 3-10 cm long 1-3 times a day.
Contraindications:
Increased sensitivity to heparin.
Side Effects:
Local reactions of hypersensitivity are possible, especially when the drug Lioton is used for a long time.
Special instructions:
It should not be used in bleeding, applied to open wounds, mucous membranes, areas of plying processes. In the development of hypersensitivity reactions, the drug is canceled and prescribed appropriate therapy.
Interaction
The drug Lioton can increase thrombone time in patients receiving indirect anticoagulants.
Overdose:
Cases of overdose are not described. As an antidote, sodium heparin is prescribed protamin sulfate.
storage conditions:
At a temperature not higher than 25 degrees Celsius.
