Instructions for No-Spa (drotaverine) 20 mg / 2 ml ampoules
Release Form No-Spa
Solution for intravenous and intramuscular administration, 20 mg/ml, ampoules of 2 ml five ampoules
Description
Transparent liquid in ampoules of greenish-yellow color.
One vial contains 20 mg of drotaverine hydrochloride in one ml of solution.
ATC Codes No-Spa
A03AD02 drotaverine
Clinical and pharmacological groups / Group affiliation
Spasmolytic drug
Active substance
drotaverine hydrochloride
Pharmacotherapeutic group No-Spa
Spasmolytic agent
Storage conditions
The drug should be stored in a place out of reach of children, protected from light at a temperature of 15-25 °C.
Pharmacological effect No-Spa
Drotaverine is an isoquinoline derivative that effectively relaxes smooth muscle. Its action is based on the blocking of the phosphodiesterase (PDE) enzyme. This enzyme is involved in the conversion of cyclic adenosine monophosphate (c-AMP) to adenosine monophosphate (AMP).
The drug is used in No-Spa
Spasms of smooth muscle associated with biliary diseases (cholecystolithiasis, cholangiolithiasis, cholecystitis, pericholecystitis, cholangitis, papillitis).
Spasms of the urinary tract smooth muscle (nephrolithiasis, urethrolithiasis, pyelitis, cystitis, bladder tenesmus).
As adjunctive therapy (when the form of tablets cannot be applied):
Gastrointestinal spasms of smooth muscle (gastric and duodenal ulcer, gastritis, cardiac and pyloric spasms, enteritis, colitis).
Gynecological diseases (dysmenorrhea).
Method of application and dosage:
Average daily dose in adults: 40-240 mg of drotaverine hydrochloride divided into one - three doses per day, intramuscularly (IM).
For acute colic (renal or cholelithiasis): 40 to 80 mg IV (IV) slowly (duration: about thirty seconds)
