Instructions for Pancreatin
Pancreatin Pharmacological properties:
Included in the preparation Pancreatin pancreatic enzymes (pancreatic enzymes) - amylase, lipase and proteazaoblegchayut digestion of carbohydrates, fats and proteins that promotes their more complete absorption in the small intestine. In diseases of the pancreas, the drug compensates for the insufficiency of its secretory function (secretion of digestive juice) and helps to improve the digestion process.
Pancreatin Indications for use:
Insufficiency of the secretory function of the pancreas (chronic pancreatitis - inflammation of the pancreas, cystic fibrosis - a hereditary disease characterized by blockage of the outlet ducts of the pancreas, glands of the respiratory tract and intestines, viscous secretion, etc.). Chronic inflammatory-dystrophic diseases of the stomach, intestines, liver, gallbladder; conditions after resection (removal of part of an organ) or irradiation of these organs, accompanied by impaired digestion of food, flatulence (accumulation of gases in the intestines), diarrhea (diarrhea) - as part of combination therapy. Condition after pancreatectomy (removal of the pancreas). Obstruction (obstruction) of the pancreatic ducts or biliary tract. To improve digestion, write in patients with normal function of the gastrointestinal tract in case of a violation of the diet, as well as in violation of the chewing function, forced prolonged immobilization (immobilization), a sedentary lifestyle. Preparation for X-ray and ultrasound examination of the abdominal organs.
Pancreatin Mode of application:
The dose of Pancreatin (in terms of lipase) depends on the age and degree of pancreatic insufficiency. The average dose for adults is 150,000 U / day. With complete insufficiency of the secretory function of the pancreas - 400,000 U / day, which corresponds to the daily requirement of an adult for lipase. The maximum daily dose is 15 GOO-20,000 U / kg of body weight.
Children under the age of 1.5 years are prescribed 50,000 U / day; over 1.5 years - 100,000 U / day.
In case of cystic fibrosis, the dose of the drug is selected individually. The dose should be adequate to the amount of enzymes required for fat absorption, taking into account the quality and quantity of food consumed.
Tablets, capsules or dragees are taken with meals, swallowed whole with plenty of non-alkaline liquid (water, fruit juices). To facilitate swallowing and improve the absorption of the drug used in capsules, especially in patients after gastric resection, you can open the capsule and swallow its contents without chewing.
The duration of treatment can vary from several days (in case of indigestion due to inaccuracies in the diet) to several months or even years (if constant substitution therapy is necessary).
Side effects:
Acute pancreatitis (inflammation of the pancreas). With prolonged use, hypersensitivity reactions are very rarely possible. In some cases, immediate allergic reactions are observed, as well as allergic reactions from the digestive tract. With prolonged use of high doses of the drug, the development of hyperuricosuria (increased content of uric acid in the urine) is possible. With cystic fibrosis, after taking large doses, sometimes there is the formation of strictures (narrowings) in the ileocecal section (the junction of the large and small intestines) and in the colon (section of the large intestine).
Pancreatin Contraindications:
Acute pancreatitis, exacerbation of chronic pancreatitis, hypersensitivity to drug components.
Release form:
Pancreatin tablets . Pancreatin capsules . Dragee Pancreatin . Gelatin capsules containing enteric-coated microtablets containing lipase 10,000, 20,000 or 25,000 units each; amylase at 9000, 18000 or 22,500 units; protease 500, 1000 or 1250 units.
Storage conditions
Store in a cool, dry place.
