Instructions for Phenazalgin
Description Phenazalgin:
Other drugs used in urology.
Composition Phenazalgin:
Active ingredient: Phenazopyridine hydrochloride.
Excipients.
Phenazopyridine
Indications for use Phenazalgin:
Symptomatic therapy for dysuria (including pain, burning, frequent urination) caused by irritation of the mucous membrane of the lower urinary tract due to infections, trauma, surgery, endoscopic procedures, the use of a tube or catheter.
Pharmacokinetics Phenazalgin:
The pharmacokinetic properties of phenazopyridine have not been fully studied. Phenazopyridine and its metabolites are rapidly excreted by the kidneys. 90% during the day when taking 600 mg of phenazopyridine per day, with 41% in the form of an unchanged drug and 49% in the form of a metabolite.
Pharmacodynamics Phenazalgin:
Phenazopyridine, excreted in the urine, acts on the mucous membrane of the lower urinary tract, where it has a local analgesic effect. This action helps to reduce dysuria including pain, burning sensation, and increased urination. The exact mechanism of action is unknown.
Contraindications Phenazalgin:
Hypersensitivity to phenazopyridine and auxiliary components of the drug;
liver dysfunction;
renal failure;
anemia and methemoglobinemia;
period of breastfeeding (safety not established);
children under 18 years of age.
With caution,
deficiency of glucose-6-phosphate dehydrogenase;
heart failure;
neuromuscular diseases;
pregnancy;
age over 65 years (no experience of use).
Side effects Phenazalgin:
Central nervous system disorders: rarely headache, dizziness, aseptic meningitis.
Disorders from the gastrointestinal tract and liver: rarely - nausea, vomiting, diarrhea; very rarely - acute hepatotoxicity (associated with drug overdose), jaundice.
Disorders from the kidneys and urine of the excretory tract: uronephrolithiasis, acute nephrotoxicity (associated with an overdose of the drug).
Immune system disorders: rarely - skin rash, itching, fever and other hypersensitivity reactions; very rarely - bronchospasm.
Allergic reactions: anaphylactoid reaction, allergic hepatitis.
Disturbances from the blood and lymphatic system: methemoglobinemia, hemolytic anemia (with a deficiency of glucose-6-phosphate dehydrogenase), sulfohemoglobinemia. neuropenia, leukopenia, pancytopenia.
Other violations: rarely - staining of feces in an orange-red color, staining of urine in a dark orange or reddish color; very rarely with long-term use - a change in the pigmentation of the skin and sclera with yellowish color, swelling of the face, upper and lower extremities; yellowing of nails, blurred vision, eye irritation, ear pain, reversible loss of color vision. Phenazalgin
Method of preparation or use Phenazalgin:
Inside, whole, after meals, with a full glass of water, do not chew the tablets. Adults: 2 tablets (200 mg) 3 times a day.
Duration of admission is no more than 2 days (including in combination with antimicrobial agents).
The efficacy and safety of Phenazopyridine when used in children under 18 and over 65 has not been established.
If you accidentally skip taking Phenazopyridine, you should take it as soon as possible, if the patient remembers the missed dose of the drug in the period immediately before taking the next dose, then you should not double it.
Vacation procedure Phenazalgin:
According to the form of the prescription form 107-1 / y
Storage conditions Phenazalgin:
Store in a dry, dark place at a temperature not exceeding 25 ° C.
