Instructions for POSTINOR (Levonorgestrel) 2 tablets
Release form
Tablets
Description POSTINOR:
The tablets are white or almost white, shaped like a disc, chamfered and engraved with a circular "INOR·" on one side.
1 tab.
levonorgestrel 750μg
Auxiliary substances: silicon dioxide colloidal, potato starch, magnesium stearate, talc, cornstarch, lactose monohydrate.
2 pcs. - blister packs (1) - cardboard packs.
ATC codes
G03AC03 Levonorgestrel
Clinical-pharmacological groups / Group affiliation
Postcoital contraceptive. Gestagen
Active substance
levonorgestrel
Pharmacotherapy group
Gestagen
Storage Conditions
The drug should be stored in a place inaccessible to children at a temperature of 15° to 25°C.
Best before date
Shelf life is 5 years.
Component contraindications:
Levonorgestrel contraindications.
Inside. Increased sensitivity to levonorgestrel; severe liver failure; pregnancy (in pm estimated); Breastfeeding period; Age up to 16 years.
For PTS. Pregnancy or suspicion. Present or recurrent inflammatory diseases of pelvic organs. Lower urinary and genital tract infections. Postpartum endometritis. Septic abortion in the last 3 months. Cervicite. Diseases. With increased susceptibility to infections. Dysplasia of the cervix. Malignant neoplasms of the uterus or cervix. Progestogenic tumours. In pm breast cancer. Pathological uterine bleeding of unclear etiology. Congenital or acquired abnormalities of the uterus. It's fibromyoma. Leading to deformation of the uterus cavity. Acute diseases or liver tumors. Increased sensitivity to levonorgestrel.
Levonorgestrel in HTS has not been studied in women over 65 years of age, so it is not recommended for this category of patients.
Use of Levonorgestrel in breastfeeding.
Testimony:
emergency (postcoital) contraception (after unprotected sexual contact or the precariousness of the contraceptive method used).
Method of use, course and dosage:
Inside. It is necessary to take 2 tables. In the first 72 hours after unprotected intercourse: Table 2. It should be taken 12 hours (but not later than 16 hours) after receiving the 1st table.
To achieve a more reliable effect, both pills should be taken as soon as possible after unprotected intercourse (no later than 72 hours).
If vomiting occurs within 3 hours after the 1st or 2nd dose of the Postinor tablet, you should take 1 more table.
Postinor can be used at any time of the menstrual cycle. In the case of irregular menstrual cycle, the pregnancy must be avoided.
Local barrier contraceptive methods (e.g. condom, cervical cap) should be used after taking the emergency contraceptive before the next menstruation. The use of the drug in the case of repeated unprotected sexual intercourse during one menstrual cycle is not recommended (due to an increase in the frequency of acyclic blood secretions / bleeding).
Overdose:
Symptoms: increased severity of side effects.
Treatment: There is no specific antidote. Symptomatic therapy is performed.
Drug interaction POSTINOR:
The simultaneous use of preparations inducing liver enzymes accelerates the metabolism of levonorgestrel.
Levonorgestrel reduces the effectiveness of hypoglycemic and anticoagulant (derivatives of coumarin, phenindion) drugs. Increases plasma concentrations of GCS. Women taking these drugs should see a doctor.
Preparations containing levonorgestrel may increase the risk of cyclosporin toxicity due to the suppression of its metabolism.
Use in pregnancy and breastfeeding
Postinor is contraindicated for use in pregnancy. If the pregnancy was caused by an emergency method of contraception, no adverse effects of the drug on the fetus have been identified on the basis of available data.
Levonorgestrel is excreted with breast milk. Breastfeeding should be stopped for 24 hours after taking the drug.
Side Effect POSTINOR:
Allergic reactions: Possibly - urticaria, rash, itching, swelling of the face.
Transient side effects, occurring at different frequencies and not requiring drug therapy: very often (≥1/10), often (≥1/100, <1/10)
On the reproductive side: Very often - abdominal pains, acyclic blood secretions (bleeding); Often - breast pain, delay of menstruation (no more than 5-7 days if menstruation is delayed for a longer period, pregnancy should be excluded).
On the digestive side: very often - nausea; Often vomiting and diarrhea.
From the nervous system: Often it is dizziness, headache.
Others: Very often, fatigue.
Contraindications for use:
increased sensitivity to drug components;
severe liver failure;
Adolescence under 16 years of age;
pregnancy;
rare inherited diseases such as lactose intolerance, lactase deficiency or glucose-galactosis malabsorption.
With caution: liver and biliary diseases, jaundice (including anamnesis), Crohn's disease, lactation.
The effectiveness of POSTINOR pills after unprotected intercourse without contraceptives decreases over time:
Time between sexual intercourse and taking POSTINOR tablets Efficiency
24 hours or less 95%
25-48 hours 85%
49-72 hours 58%
The drug does not replace the use of permanent methods of contraception. In most cases, POSTINOR does not affect the menstrual cycle. However, acyclic blood secretions may occur and menstruation may be delayed by several days. If menstruation is delayed by more than 5-7 days and the character of menstruation changes (scarce or abundant discharge), pregnancy should be excluded. The appearance of lower abdominal pain, fainting conditions may indicate ectopic pregnancy.
In exceptional cases (including rape), adolescents under 16 need a gynaecologist to confirm pregnancy.
After emergency contraception, a gynaecologist's consultation was recommended to determine the most appropriate method of permanent contraception.
Emergency contraception does not protect against sexually transmitted diseases.
In case of disorders of the GI tract (for example, in case of Crohn's disease), the effectiveness of the drug may be reduced.
Influence on the ability to control vehicles and machinery
POSTINOR influence on the ability to drive motor vehicles and machinery has not been studied.
Application for kidney disorders
Data on the use of the drug in patients with kidney disorders was not provided.
Use in liver disorders
The drug is carefully prescribed to patients with liver and biliary tract diseases, contraindicated in severe liver failure.
Terms of Sale
The drug is prescription.
Use in children
The drug is contraindicated in adolescence to 16 years.
Nosology (ICD codes)
Z30.0
General advice and counselling on contraception