Instructions for Pulmibud (Budesonide) ampoules
English Product Name
Pulmibud
Dosage form Pulmibud
susp. d / inhalation dosed 250 μg / ml: 2 ml amp. 20 pcs.
susp. d / inhalation dosed 500 μg / ml: 2 ml amp. 20 pcs.
Description
Suspension for inhalation dosed white, homogeneous.
1 ml
budesonide 250 mcg
Excipients: disodium edetate, sodium chloride, polysorbate 80, citric acid anhydrous, sodium citrate, water for / and.
2 ml - polyethylene ampoules, soldered together in the form of a block (5) - envelopes made of aluminum foil (4) - cardboard packs.
ATX Codes
R03BA02 Budesonide
Clinical and pharmacological groups / Group affiliation
GCS for topical use
Active ingredient Pulmibud
budesonide
Pharmaco-therapeutic group
Glucocorticosteroid for topical use
pharmachologic effect Pulmibud:
GCS with a pronounced local anti-inflammatory and antiallergic effect. Budesonide increases the production of lipocortin, which is an inhibitor of phospholipase A2, inhibits the release of arachidonic acid, inhibits the synthesis of leukotrienes and prostaglandins, reduces inflammatory exudation and cytokine production, inhibits the migration of macrophages, reduces the severity of infiltration and granulation processes, the formation of the substance chemotaxis (which explains the effectiveness in delayed hypersensitivity reactions), inhibits the release of mediators from mast cells inflammation (immediate hypersensitivity reaction).
Testimony Pulmibud:
- Treatment of bronchial asthma (as a basic therapy;
- with insufficient effectiveness of beta2-adrenomimetics;
- to reduce the dose of oral corticosteroids);
- treatment of COPD;
- stenosing laryngotracheitis (false croup).
Dosage, Course and Dosage:
Budesonide Steri-Neb is used inhalation using nebulizer inhalers (see below - "Technique of use").
Recommended doses of the drug in case of initiation of inhalation GCS therapy in severe bronchial asthma, as well as against the background of dose reduction or discontinuation of oral corticosteroids for adults (including the elderly) and children over twelve years of age - one mg twice / day, maintenance dose - 0.5-4 mg / day; for children from six months to twelve years of age - 0.25-0.5 mg twice a day maintenance dose - 0.25-two mg / day. In the event that the recommended dose does not exceed 1 mg / day, the entire dose of the drug can be taken at a time (at a time).
Use in case of impaired liver function Budesonide
With caution, the drug should be prescribed for cirrhosis of the liver.
Use in elderly patients
There are no indications for limiting use in elderly patients.
Use in children Budesonide
Contraindicated in children under the age of 6 months. Use in older children is possible in dosage forms intended for this category of patients.
- Nosology Pulmibud (ICD codes)
- J05.0
- Acute obstructive laryngitis [croup]
- J44
- Another chronic obstructive pulmonary disease
- J45
- Asthma
