Buy Rosuvastatin-SZ tablets

Rosuvastatin-SZ tablets

22337USD

Description

Features

Reviews

Instructions for Rosuvastatin-SZ tablets

Description rosuvastatin

Pink-colored film-coated tablets are round and double-convex; cross-sectioned, the nucleus of the tablet is white or almost white.

ATC Codes
C10AA07 - Rosuvastatin

Pharmacological groups rosuvastatin

The preparation relates to lipid-lowering agents and is also an inhibitor of the enzyme HMG-CoA reductase.

Active substance rosuvastatin
The main active ingredient of the preparation is rosuvastatin, which is in the form of a calcium salt.

Purpose
The drug is used to lower lipid levels in the blood and belongs to the group of lipid-lowering drugs.

Storage conditions rosuvastatin
The drug should be stored away from children and away from direct sunlight. The storage temperature shall not exceed 25 °C.

Pharmacological effect

Rosuvastatin is a drug that lowers blood lipid levels and functions as a selective and competitive inhibitor of the HMG-CoA reductase enzyme. This enzyme is responsible for the conversion of 3-hydroxy-3-methylglutaryl coenzyme A into mevalonic acid, which is the precursor of cholesterol.

The main goal of rosuvastatin is the liver, where cholesterol is synthesized and low-density lipoprotein (LDL) is metabolized. The drug increases the number of LDL receptors on the liver cell surface, which actualizes the capture and destruction of LDL. This process results in decreased synthesis of very low density lipoprotein (VLDL), ultimately resulting in decreased total LDL and VLDL levels in the body.

Indications rosuvastatin

Primary hypercholesterolemia, classified by Fredrickson type IIa (including heterozygous seminal hypercholesterolemia) or mixed hypercholesterolemia (type IIb), in addition to
dietary treatment, when dietary and other nondrug measures (such as physical activity and weight loss) fail;
Familial homozygous hypercholesterolemia combined with diet and lipid-lowering therapy (eg, LDL apheresis) or in situations where such therapy is inadequate
hypertriglyceridemia (Fredrickson type IV) as an adjunct to nutritional support;
to slow atherosclerotic changes in the vascular system as an adjunct to the diet in patients who require therapy to reduce overall cholesterol and LDL cholesterol;
primary prevention of serious cardiovascular diseases (heart attack, stroke, arterial revascularization) in adults with increased risk but no clinical signs of CHD (men over 50 years,
women over 60 years, elevated C-reactive protein (> 2 mg/L) in the presence of at least one of the additional risk factors, such as hypertension, low HDL, smoking, family history
of early CHD).

Instructions for use, course and dosage

The drug is taken by mouth at any convenient time, regardless of food intake. The pill should be swallowed whole, without chewing, drinking enough water.

Before starting Rosuvastatin-RD therapy, the patient should follow a standard hypocholesterolemic diet. Dieting is recommended during treatment. The dosage is selected individually, taking into account the goals of therapy and the body's response to treatment. It is important to be guided by current recommendations for lipid targets.