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Simvastatin 28 pills

SKU:2251
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Simvastatin patients with ischemic heart disease or at high risk of coronary artery disease, reducing the risk of all-cause mortality by reducing mortality due to coronary artery disease
Active substance:Simvastatin
Pharmacological group:Cardiac medications
Formulation:Tablets
Pills in 1 package:28
In stock
$9
11
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Instructions for Simvastatin pills

English product name
Simvastatin

Release form

tab, shell, 10 mg: 20 pcs
tabp., shell, 20 mg: 20 pcs
Description
The tablets are covered with a shell of white color, round, double-convex, with a risk on one side.

1 tab.
simvastatin 10 mg
Auxiliary substances: lactose, pregelatinized starch, microcrystalline cellulose, talc (magnesium hydrosilicate), magnesium stearate, butyl hydroxyanisole.

The shell consists of a hyprolose (hydroxypropyl cellulose), a hypromellose, titanium dioxide (E171) and talc (magnesium hydrosilicate).

10 pcs - blister packs (2) - cardboard packs.

ATC codes
C10AA01 Simvastatin

Clinical-pharmacological groups / Group affiliation
Hypolipidemic drug

Active substance
simvastatin

Pharmacotherapy group Simvastatin

Hypolipidemic agent - reductase inhibitor GMG-CoA

Storage Conditions
Keep away from children at 15° to 25°C.

Best before date
The shelf life is two years.

Pharmacological effect Simvastatin

The hypolipidemic preparation produced synthetically from the fermentation product Aspergillus terreus is an inactive lactone, in the body is hydrolyzed to form a hydroxy-acid derivative. The active metabolite inhibits 3-hydroxy-3-methyl-glutaryl-CoA reductase (GMG-CoA reductase), an enzyme that catalyzes the initial formation of mevalonate from GMG-CoA.

Testimony Simvastatin

Hypercholesterolemia:

primary hypercholesterolemia (type IIa and IIb) in the case of failure of low-cholesterol dieting and other non-medicamentous interventions (exercise and body weight reduction) in patients with
increased risk of coronary atherosclerosis;
combined hypercholesterolemia and hypertriglyceridemia, not corrected by special diet and exercise.
Coronary heart disease:

for prevention of myocardial infarction, for reduction of the risk of death, reduction of the risk of cardiovascular disorders (stroke or transient ischemic attacks), slowing the progression of atherosclerosis coronary vessels, reduction of the risk of revascularization procedures.

Method of use, course and dosage Simvastatin

Prior to treatment with simvastatin, the patient should be given a standard hypocholesterone diet which should be followed throughout the course of treatment.
Simvastatin should be ingested once a day in the evening, drinking enough water.

The time of taking the drug should not be associated with eating. The recommended dose of simvastatin for the treatment of hypercholesterolemia ranges from lesyati to eighty mg once a day in the evening. The recommended initial dose for hypercholesterolemia patients is 10 mg. The maximum daily dose is 80 mg.

Dose changes (selection) should be carried out at intervals of four weeks. In most patients, the optimal effect is achieved when taking the drug in doses of up to twenty mg per day.

Terms of Sale
The drug is prescription.

Application in elderly patients
In older patients, no changes in dosage of the drug are required.

Use in children
Contraindication: Age up to eighteen years (effectiveness and safety are not established).

  • Nosology Simvastatin (ICD codes)
  • E78.0
  • Pure hypercholesterolemia
  • E78.1
  • Pure hyperglyceridemia
  • E78.2
  • Mixed hyperlipidemia
  • G45
  • Transitory cerebral ischemic attacks [attacks] and related syndromes
  • I21
  • Acute myocardial infarction
  • I25.1
  • Atherosclerotic heart disease
  • I61
  • Intracerebral hemorrhage (haemorrhagic type disorder)
  • I63
  • Brain infarction
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