Instructions for Tantum Rosa (Benzydamine)
Active ingredients Tantum Rosa:
Benzydamine
Release form Tantum Rosa:
Solution / powder for preparation of vaginal solution
Composition:
Active ingredient: benzydamine (in hydrochloride form) Concentration of active ingredient (mg): 1 mg.
Pharmacological effect Tantum Rosa:
NSAIDs for topical use, belongs to the indazole group. Benzydamine has antibacterial, anti-inflammatory, antiexudative and analgesic effects, as well as histoprotective activity. The mechanism of action of the drug is associated with the stabilization of cell membranes and inhibition of prostaglandin synthesis. Benzydamine has an antibacterial effect due to the rapid penetration of microorganisms through the membranes with subsequent damage to cellular structures, cell lysis. It has an antifungal effect against Candida albicans. It causes structural modifications of the cell wall of fungi and metabolic chains of mycetes and thus prevents their reproduction.
Pharmacokinetics:
When applied topically, the drug is well absorbed through the mucous membranes and penetrates into inflamed tissues. Benzydamine is excreted mainly by the kidneys and through the intestines in the form of metabolites or conjugation products. Benzydamine in topical dosage forms does not have a systemic effect and does not penetrate into breast milk.
Indications Tantum Rosa:
Tantum Rosa is prescribed for: - vaginosis associated with a bacterial infection; - vulvovaginitis of a specific nature (in treatment regimens); - vulvovaginitis of a nonspecific nature; - inflammatory diseases in gynecology associated with the passage of radiotherapeutic, chemotherapeutic treatment; - cervicovaginitis; - various etiology prophylaxis inflammation and infection in surgical gynecology (used before, after surgery); - hygiene during the period after childbirth.
Contraindications Tantum Rosa:
is not prescribed for
indications in pediatrics (up to 12 years)
hypersensitivity to the active ingredient
hypersensitivity to additive components of the dosage form.
Precautions
Do not exceed recommended doses.
Application during pregnancy and lactation
There are no contraindications to the local use of Tantum Rosa during pregnancy and lactation (breastfeeding).
Method of administration and dosage Tantum Rosa:
Tantum rosa is indicated for intravaginal use. When using powder, it is necessary to dilute the contents of 1 sachet in 0.5 l of pure water. The resulting solution is used in the same way as Tantum rosa in the form of a solution. For one douching, it is necessary to use about 140 ml of the finished dosage form. When using a solution from a vial, it is shown to use all its contents at one time for douching. The bottle is kept in a water bath to warm up to body temperature. The introduction of the medicinal fluid is carried out in the supine position. It is necessary to ensure the retention of the medicinal solution in the vagina for several minutes. Treatment regimens for various indications: Indication, condition Course, days Frequency rate, times / day Vaginosis associated with bacterial infection 7-10 1-2 Vulvovaginitis,
Side effects:
In the official documentation, the occurrence of adverse reactions during therapy with Tantum rosa was not reported. It is theoretically possible to develop hypersensitivity reactions.
Overdose Tantum Rosa:
Currently, no cases of overdose of the drug have been reported.
Interaction with other drugs
Clinically significant drug interactions with have not been established. special instructions
Do not use the drug for a long time, because this can cause the development of hypersensitivity reactions. If during the recommended course of treatment there is no therapeutic effect, then the patient should consult a doctor.Effect on the ability to drive vehicles and control mechanisms
The use of the drug does not affect the ability to drive vehicles and other potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions
