Instructions for Thiogamma (Thioctic acid) pills
English product name
Thiogamma
Release form
tab, film coating, 600 mg: 30, 60 or 100 pcs
Description Thiogamma:
The film-coated tablets are oblong, double-convex, with a smooth and slightly shiny surface, with a single separation risk on both sides, yellow with possible white and dark yellow impurities.
1 tab.
thioxic acid 600 mg
Auxiliary substances:
hypromellose - 25 mg, silicon dioxide colloid - 25 mg, cellulose microcrystalline (type PH112) - 49 mg, lactose monohydrate - 49 mg, sodium croscarmellose - 16 mg, talc - 36.364 mg, dimethicone - 3.636 mg, magnesium stearate - 16 mg.
Shell Composition:
macrogol 6000 - 0.6 mg, hypromellose - 2.8 mg, talc - 2 mg, sodium lauryl sulfate - 0.025 mg.
ATC codes
A16AX01 Thioctic acid
Clinical-pharmacological groups / Group affiliation
Metabolic drug Thioctic acid
Active substance
thioxic acid
Pharmacotherapy group:
Metabolic agent
Storage Conditions
The drug should be stored in a place inaccessible to children at a temperature not higher than 25 ° C.
Best before date
Shelf life is 3 years. Do not use after the expiry date specified on the package.
Testimony Thiogamma:
diabetic polyneuropathy;
alcoholic polyneuropathy.
Method of use, course and dosage:
The drug Thioctic acid is administered orally at 600 mg (one tablet) once a day. The tablets are taken on an empty stomach, not chewing, sucking in a small amount of liquid.
The duration of treatment is 30-60 days depending on the severity of the disease. The treatment may be repeated two to three times a year.
Pharmacological effect Thiogamma:
Thiotic acid is an endogenous antioxidant (binds free radicals).
In the body is formed during oxidative decarboxylation of alpha-keto acids.
As a coenzyme of mitochondrial multi-enzyme complexes, it is involved in oxidative decarboxylation of pyruvic acid and alpha-keto acids. It contributes to a reduction in blood glucose concentration and an increase in glycogen in the liver, as well as a reduction in insulin resistance.
It is involved in regulating lipid and carbohydrate metabolism, affects cholesterol exchange, improves liver function, has a detoxifying effect in the case of heavy metal salts poisoning and other intoxications. It has hepatoprotective, hypolipidemic, hypocholesteryemic and hypoglycemic effects. Improves neuron trophic.
In diabetes mellitus, Thioctic acid reduces formation of final glycating products, improves endonovral blood flow, increases glutathione content to physiological value, which as a result leads to improvement of functional state of peripheral nerve fibers in diabetic polyneuropathy.
Terms of Sale
The drug Thioctic acid is prescription.
Use in children
The use of the preparation in the age of up to 18 years is contraindicated.
Nosology Thiogamma (ICD codes)
G62.1
Alcoholic polyneuropathy
G63.2
Diabetic polyneuropathy
