Instructions for Thiolepta (Thioctic acid)
English product name
Thiolepta
Release form
tab., film wallpaper., 600 mg: 30 or 60 pcs
Description:
Coated tablets 1 tab.
thioxic acid 600 mg
ATC codes
A16AX01 Thioctic acid
Clinical-pharmacological groups / Group affiliation
Preparation regulating lipid and carbohydrate exchange
Active substance Tiolepta
thioxic acid
Pharmacotherapy group:
Metabolic agent
Description Thioctic acid:
Transparent, yellow or greenish-yellow solution.
Form of release
Solution for injection
How to take the drug:
The preparation is intended for preparation of intravenous infusion solution after preliminary dilution in 09% solution of sodium chloride. one ampoule of the preparation with volume of 10 ml contains 300 mg of thiotic acid.
At the beginning of treatment, the drug Tiolepta is administered intravenously droplet in a daily dose of 600 mg (two ampoules with a volume of 10 ml).
Prior to use Tiolepta, the contents of two ampoules with a volume of ten ml are diluted in a 250 ml 09% solution of sodium chloride and administered intravenously and slowly at a rate of not more than two ml/min. The preparation has light sensitivity in connection with which the solution for infusions is prepared immediately before use. During the infusion, the bottle Thioctic acid with the solution is protected from light.
The prepared solution should be stored in a place protected from light and used for 6 hours after cooking.
The course of therapy is two to four weeks. Next, you should switch to a supportive therapy - taking of Thiotic acid in the form of tablets in a daily dose of 600 mg. The duration of the treatment and the need to repeat it is determined by the doctor.
Applied inside and in / in (struyno slowly or drip). The recommended dose is six hundred mg / day. The method of application, the therapy regimen and the duration of the course of treatment are set individually, depending on the severity of the disease.
Testimony Thiolepta:
- Diabetic polyneuropathy.
- Alcoholic polyneuropathy.
Application in elderly patients
B/C of thiotic acid should be administered with caution in patients older than 75 years of age.
Use in children
Use in children and adolescents under the age of eighteen years is contraindicated.
Nosology Thioctic acid (ICD codes)
G62.1
Alcoholic polyneuropathy
G63.2
Diabetic polyneuropathy
Pharmacological effect Thiolepta:
It is an endogenous antioxidant that binds free radicals. Thiotic (α-lipoic) acid is involved in mitochondrial metabolism of the cell, it performs the function of coenzyme in the complex of transformation of substances with a pronounced antitoxic effect.
They protect the cell from reactive radicals that occur during intermediate metabolism or during the breakdown of exogenous foreign substances, and from heavy metals.
Thiotic acid is synergistic with insulin, which is associated with increased glucose utilization. In diabetic patients, thiotic acid leads to a change in the concentration of pyruvic acid in the blood.
