Description:
In the treatment of intoxication, it is necessary to create an excess of Activated charcoal in the stomach (before washing it) and in the intestine (after washing the stomach). A decrease in the concentration of Activated charcoal in the medium contributes to the desorption of the bound substance and its absorption (to prevent resorption of the released substance, it is recommended to re-wash the stomach and administer Activated charcoal). The presence of food masses in the gastrointestinal tract requires the introduction of high doses, since the contents of the gastrointestinal tract is absorbed by Activated charcoal and its activity is reduced.
Composition:
One tablet contains:
Active ingredient: - Activated charcoal - 250 mg. Excipient: potato starch - 47 mg.
Indications:
It is used as a detoxifying agent for exogenous and endogenous toxicoses of various nature. In the complex treatment of foodborne diseases, salmonellosis, dysentery. In case of poisoning with drugs (including psychotropic, sleeping pills, narcotic drugs), alkaloids, salts of heavy metals and other poisons. In diseases of the gastrointestinal tract, accompanied by dyspepsia, flatulence. With food and drug allergies. When hyperbilirubinemia (viral hepatitis and other jaundice). With hyperazotemia (renal failure). To reduce gas formation in the intestine before ultrasound and X-ray examination.
Pharmacodynamics:
It has enterosorbing, detoxification and antidiarrheal effects. It belongs to the group of polyvalent physico-chemical antidotes, has a large surface activity.
It adsorbs poisons and toxins from the gastrointestinal tract prior to their absorption, including alkaloids, glycosides, barbiturates and other hypnotics and drugs, salts of heavy metals, toxins of bacterial, plant, animal origin, derivatives of phenol, hydrocyanic acid, sulfonamides, gases.
The drug also adsorbs an excess of certain metabolic products - bilirubin, urea, cholesterol, as well as endogenous metabolites responsible for the development of endogenous toxicosis.
Weakly adsorb acids and alkalis (including iron salts, cyanides, malathion, methanol, ethylene glycol). Active as a sorbent in hemoperfusion.
Does not irritate the mucous membrane of the gastrointestinal tract. Pharmacokinetics Not absorbed, not cleaved, completely secreted through the gastrointestinal tract within 24 hours.
Side effects:
Dyspepsia, constipation or diarrhea, staining of feces in a dark color. With prolonged use (more than 14 days) may reduce the absorption of vitamins, calcium and other nutrients from the gastrointestinal tract.
Special conditions:
If the poisoning is caused by substances involved in the enterohepatic circulation (cardiac glycosides, indomethacin, morphine and other opiates), you need to use activated charcoal for several days.
When using the drug for more than 10-14 days, prophylactic administration of vitamins and calcium preparations is necessary.
It is recommended to store in a dry place separately from substances emitting gases or vapors into the atmosphere.
Storage in air (especially wet) reduces the sorption capacity. Influence on ability to steer vehicles, mechanisms
The use of the drug does not affect the ability to perform potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions (driving, working with moving mechanisms, the work of the dispatcher and the operator).
Contraindications:
Exacerbation of gastric ulcer and duodenal ulcer, ulcerative colitis, bleeding from the gastrointestinal tract, intestinal atony, individual intolerance to the drug, simultaneous administration of antitoxic drugs, the effect of which develops after absorption (methionine, etc.).
Use during pregnancy and during breastfeeding. It is possible to use the drug during pregnancy and during breastfeeding, if the expected benefit to the mother outweighs the potential risk to the fetus and child.
Drug Interactions:
Activated charcoal reduces the effectiveness of simultaneously taken drugs, reduces the effectiveness of drugs that act on the mucous membrane of the gastrointestinal tract (including ipecac and thermopsis).
Dosage:
Apply inside in tablets or, after preliminary crushing, in the form of a water suspension, in an hour to food and reception of other medicines.
The required amount of the drug is diluted in ½ cup of water. Dosage regimen: Adults are prescribed on average 1.0-2.0 g (4-8 tablets) 3-4 times a day.
The maximum single dose for adults to 8.0 g (16 tablets). For children, the drug is prescribed on average at the rate of 0.05 g / kg 3 times a day, depending on body weight.
The maximum single dose - up to 0.2 g / kg body weight. The course of treatment for acute diseases - 3-5 days, with allergies and chronic diseases - up to 14 days.
Repeated course after 2 weeks on the recommendation of a doctor. In case of acute poisoning, treatment begins with gastric lavage, with the use of activated charcoal mist, then 20-30 g of the drug is given inside. When flatulence is prescribed inside of 1.0-2.0 g (4-8 tablets) 3-4 times a day. The course of treatment is 3-7 days.
Overdose:
To date, overdose cases have not been reported.
