Instructions for Albendacid (Albendazole) pills
Description Albendazole
Oval double-convex tablets, covered with a film shell of white color, on the cross section are visible two layers, a core of almost white color
Active substances Albendazole
Albendazol
Release Form Albendazole
Tablets
Composition
One tablet contains:
active substance: albendazol - 400.0 mg,
Auxiliary substances: corn starch, sodium croskarmellosis (sodium carboxymethyl cellulose), crossovidone (type A), povidone K 30, sodium lauryl sulfate, magnesium stearate, cellulose microcrystalline (type 101), Opadray II series 32 (F) code 280000 (white): (hypromellose, lactose monohydrate, macrogol 4000 (polyethylene glycol), titanium dioxide, E 171).
Pharmacological effect Albendazole
Anti-helmintic and anti-acid agent
Albendazole belongs to the carbamatbenzimidazole group.
The mechanism of action of albendazole is its ability to disrupt the activity of the microtubular system of cells of the intestinal channel of helminths, while causing damage to the tubulin protein. The result is biochemical disturbances in the cell: the suppression of glucose transport and fumaratreductase, which is the basis of the suppression of cell division at the stage of metaphase, and which is associated with the suppression of egg laying and the development of helminths larvae.
Testimony Albendazole
Nematodoses:
- ascaridosis, arousal - Ascaris lumbricoidesl round helminths,
- Trichocephalesis (Vlacanthus), arousal - Trichocephalus trichiurus round helminths,
- enterobiosis (oysters), arousal - Enterobius vermicularis round helminth,
- ankylostomidoses (head), exciters - Ancylostoma duodenale and Necator americanus,
- trichinellosis, causative agent - Trichinella spiralis,
- toxocarosis, causative agent - Toxocara canis,
- lambliosis, excitatory - Giardia intestinalis,
- Strogiloidosis (intestinal acne), the causative agent - Strongiloides strcoralis round helminthas, and mixed invases.
- Tissue Cestodises:
- neurocysticercosis, causative agent - Cysticercus cellulosus, larval stage of the ribbon parasite of the pig chain,
- hydatidotic echinococcosis of the liver, lungs of the abdomen caused by the larval form of the canine tapeworm (Echinococcus granulosus),
- The drug is also used as an aid for surgical treatment of alveolar echinococcosis, and the causative agent is Echinococcus multilocularis.
Method of use and doses Albendazole
The drug is taken internally, during or after ingestion. Special training and diet is not required.
The dose of the antihelmintic preparation is set individually, depending on the type of infusion, it all depends on the patient's body weight.
The maximum daily dose is 800 mg.
In children, high doses of albendazole should be avoided for a long time if possible.
For nematodoses (including ascaridosis, trichocephalosis, necatorosis) albendazole is given to patients with a body mass of six ten kg and more than 400 mg per day once, to patients with a body mass of less than six ten kg - fifteen mg/kg of body weight once or in two doses.
- Giardiasis Albendazole [lambliosis]
- B60
- Other protozoa not classified elsewhere
- B66.0
- Opispirkhoz
- B67
- Echinococcosis
- B69
- Cysticercosis
- B76
- Ankylostomidosis
- B77
- Ascaridosis
- B78
- Strongyloidosis
- B79
- Trikhuroz (trichocephalesis)
- B80
- Enterobiosis