Cervikon-Dim (Diindolylmethane) vaginal suppositories 100 mg
English product name
Cervicon-DIM
Release form
Rectal suppositories
Description Cervikon-Dim:
The product has vaginal suppositories ranging from light pink to yellowish pink in torpedo shape.
1 sp.
diindolylmethane 100 mg
Auxiliary substances: Solid fat (Vitepsol N-15) - 1.9795 g, Crospovidone (collydon CL) 0.0200 g, red carmine dye E120 0.0005 g
5 pcs. - box-type contour (3) packages - cardboard packs.
ATC codes
L01XX Other anti-tumor drugs
Active substance
diindolylmethane
Pharmacotherapy group
Antitumoral agent
Testimony Cervikon-Dim:
- Treatment of cervical dysplasia (cervical intraepithelial neoplasia)
- (regardless of the results of PCR detection).
Method of use, course and dosage:
Intravaginally twice a day.
The duration of treatment is determined on the basis of the dynamics of clinical and laboratory indicators.
Special Instructions Cervikon-Dim
It is advisable to start treatment after menstruation.
During treatment, it is recommended to refrain from sexual contact.
It is recommended to use contraception during treatment.
Use in children Cervikon-Dim
It is contraindicated in children and adolescents under the age of eighteen.
- Nosology (ICD codes)
- N87
- Cervical dysplasia
Pharmacological effect Cervikon-Dim:
It stimulates the apoptosis of human papillomavirus (HPV)-infected and transformed cells, and stimulates the expression of receptors to u-interferon. The therapeutic effect of diindolylmethane is thus based on its ability to accelerate the elimination of human papillomavirus-infected and transformed cells and to strengthen the non-specific immune response to infection. In addition, diindolylmethane normalizes estradiol metabolism in HPV-infected cells, preventing the formation of a carcinogenic estrogen metabolite (16α-hydroxyestrone) that stimulates the expression of HPV oncogenes. By suppressing the expression of the human papillomavirus oncogene E7, diindolylmethane inhibits hormone-dependent pathological proliferation of HPV-infected cells.