Instructions for Chlorhexidine solution
Form of release
r-r d/outside. Note. 0.5%: fl. 50 ml, 70 ml or 100 ml; bottles of 200 ml, 250 ml, 500 ml and 1 l; canisters 1 l, 3 l, 5 l, 10 l, 20 l
The solution for external use is colorless or slightly yellowish, transparent or slightly opalescent, with a characteristic smell of alcohol.
chlorhexidine bigluconate (20% r-r) 25 ml
which corresponds to the content of chlorhexidine bigluconate 5 g
Excipients: ethanol (ethyl alcohol 95%) - 718.5 ml, purified water - up to 1000 ml.
Clinical-pharmacological groups / Group affiliation
Antiseptic for outdoor and local use
Pharmacological effect Chlorhexidine solution
Antiseptic agent with mainly bactericidal effect. Chlorhexidine, depending on the concentration used, exhibits bacteriostatic or bactericidal action against gram-positive and gram-negative bacteria. The bacteriostatic effect is manifested in a concentration of 0.01% or less; bactericidal - at a concentration of 0.01% at a temperature of 22 ° C and exposure for 1 minute; fungicidal action at a concentration of 0.05%, a temperature of 22°C and exposure for 10 minutes; virulicidal action (for lipophilic viruses) is manifested at a concentration of 0.01-1%.
Bacteria spores are only affected at elevated temperatures. It is stable, and after treatment the skin is preserved on it in some amount sufficient for the appearance of a bactericidal effect. It remains active (though somewhat reduced) in the presence of blood, pus, various secretions and organic matter.
Does not damage items made of glass, plastic or metals.
Testimony Chlorhexidine solution:
As a therapeutic and prophylactic agent for various infections, for aseptic treatment and disinfection.
Hygienic treatment of the hands of medical personnel, the hands of surgeons, for the treatment of the skin of the operating and injection fields, the elbow bend of the donor; disinfection of small surfaces of medical products, including dental instruments (heat treatment of which is undesirable) in medical institutions. Hygienic treatment of hands in medical and prophylactic institutions. Hygienic treatment of hands of medical personnel of institutions of various profiles and purposes.
Method of use, course and dosage:
The dose and method of use depend on the indications and dosage form of chlorhexidine.
The conformity of the used dosage form with the indications for use should be strictly observed.
Drug Chlorhexidine solution interaction
Not used in combination with anion compounds, including soap.
It is incompatible with carbonates, chlorides, phosphates, borates, sulphates and citrates.
Application of hard water reduces bactericidal properties.
It is compatible with medicines containing the cationic group (benzalkonium chloride, citramonia bromide).
Use in pregnancy and breastfeeding
If use is necessary during pregnancy and during breastfeeding, the expected benefit of the therapy for the mother and the possible risk for the foetus should be weighed.
Side Effect Chlorhexidine solution:
Allergic reactions: skin rash, itching.
From the skin and subcutaneous fat: dry skin, itching, dermatitis, photosensitization.
Contraindications for use
Increased sensitivity to chlorhexidine.
Chlorhexidine should not be allowed to enter the eyes (except in a special form intended for ophthalmology), and contact with the brain and auditory nerve.
Use in children
Use with caution in children.
Nosology (ICD codes)
Preparatory procedures for follow-up treatment or examination not classified elsewhere