Instructions for Clindacin (Clindamycin) vaginal cream
Description:
for topical use in gynecology.
Composition Clindacin:
Clindamycin Phosphate 100 mg
Excipients: sodium benzoate, castor oil, 1,2-propylene glycol, polyethylene oxide (as an emulsifier).
Indications for use: Clindacin:
Bacterial vaginosis caused by microorganisms sensitive to the drug.
Pharmacokinetics:
After a single intravaginal injection of 100 mg of, an average of 4% of the administered dose undergoes systemic absorption. Cmax of clindamycin in blood plasma is 20 ng / ml.
Pharmacodynamics:
lincosamide group for vaginal use. The mechanism of action of the drug is associated with a violation of intracellular protein synthesis in a microbial cell at the level of the 50S ribosome subunit.
has a broad spectrum of action, has a bacteriostatic effect, in higher concentrations against some microorganisms - bactericidal. It is active against microorganisms that cause bacterial vaginosis: Gardnerella vaginalis, Mobiluncus spp., Bacteroides spp., Mycoplasma hominis, Peptostreptococcus spp. Trichomonas vaginalis and Candida albicans are not sensitive to.
Contraindications:
Hypersensitivity to clindamycin or lincomycin.
Side effects Clindacin:
The development of allergic reactions, the appearance of irritation at the injection site, cervicitis, vaginitis, vulvovaginal candidiasis is possible.
Method of preparation or use Clindacin:
Introduced intravaginally using an applicator.
The recommended single dose is 100 mg (one full applicator), preferably at bedtime for 3-7 days.
Vacation procedure:
According to the form of prescription form 107-1 / y
