Cocarnit Lyophilisate (Triphosadenine) for solution preparation, 3 ampoules

Instructions for Cocarnit Lyophilisate (Triphosadenine) for solution preparation, 3 ampoules

Active substances Triphosadenine
Trifonadenin

Release form Cocarnit
Solution for injection

Pharmacological effect Cocarnit:

The drug Triphosadenine is a rationally selected complex of metabolic substances and vitamins.

Tribosadenine is a derivative of adenosine that stimulates metabolic processes. It has vasodilating effects, including coronary and brain arteries. Improves metabolism and energy supply of tissues. It has hypotensive and antiarrhythmic effects. After parenteral administration, it enters organ cells where it is broken down into adenosine and inorganic phosphate, releasing energy. Subsequently, cleavage products are incorporated into ATP synthesis. Under the influence of ATP occurs a reduction in AD, relaxation of smooth muscles, improved performance of nerve impulses.

Cocarboxylase is a coenzyme that is formed in the body from the external thiamine (vitamin B1). It is a carboxylase enzyme that catalyzes carboxylation and decarboxylation of α-keto acids. Indirectly promotes the synthesis of nucleic acids, proteins and lipids. It reduces the concentration of milk and pyrogrape acids in the body, promotes glucose uptake. Improves the trophic of nervous tissue.

Cyanocobalamin (vitamin B12) in the body is converted to methylcobalamin and 5-deoxyadenosylcobalamin. Methylcobalamin is involved in the conversion of homocysteine to methionine and S-adenosylmethionine, the key metabolic responses of pyrimidine and purine bases (and hence DNA and RNA). If the vitamin is insufficient in this reaction, it can be replaced by methyltetrahydrofolic acid, thus disrupting the folate-dependent metabolic reactions.

5-deoxyadenosylcobalamine serves as a cofactor in the isomerization of L-methylmalyl-CoA to succinyl-CoA, an important metabolic reaction of carbohydrates and lipids.

Vitamin B12 deficiency leads to impaired proliferation of rapidly dividing cells of the hematopoietic tissue and epithelium, as well as impaired myelin sheath formation.

Nicotinamide is a form of vitamin PP, is involved in oxidative-reducing processes in the cell, improves carbohydrate and nitrous exchange, regulates tissue respiration.

Testimony Cocarnit:

• Symptomatic treatment of diabetic polyneuropathy.

Use in pregnancy and breastfeeding
It is not recommended to use the drug Cokarnit during pregnancy. It is recommended to stop breastfeeding during treatment.

Method of use and doses Triphosadenine:

Inside m (in the gluteal muscle). The drug Triphosadenine is injected deeply.
In cases of severe pain syndrome, it is advisable to start treatment with the insertion of one amp. (two ml per day) until acute symptoms are relieved. Duration of application - nine days.

After improving symptoms or in cases of mild symptoms of polyneuropathy: Two to three times a week for two to three weeks. The recommended course of treatment is three to nine injections, depending on the severity of the disease. The duration of treatment and follow-up is determined by the doctor depending on the nature and severity of the disease.

Children. Data on the effectiveness and safety of the use of Cocarnit in children are not available