Instructions for Daivobet (calcipotriol, betamethasone) ointment
Active substance (INN)
betamethasone
ATC codes
D05AX52 (Calcipotriol in combination with other drugs)
Nosology, ICD Codes Daivobet
L40... (Psoriasis)
Description Daivobet
The ointment for external use is uniform, from almost white to pale yellow.
1g
betamethasone dipropionate 643μg,
&emsp,betamethasone equivalent 500μg
calcipotriol monohydrate 52 ug,
&emsp,equivalent to calcipotriol 50μg
Auxiliary substances: paraffin liquid (contains about 10 ppm alpha-tocopherol) - 30 mg, polypropylene glycol stearate (contains about 0.1% butyl hydroxytoluene) 50.0 mg, alpha-tocopherol 0.02 mg, paraffin white soft (contains about 10 ppm alpha-tocopherol) up to 1.0 g.
15 g - aluminium tubes (1) - cardboard packs.
30 g - aluminium tubes (1) - cardboard packs.
60 g - aluminium tubes (1) - cardboard packs.
Release Form
ointment d/external approx. 500 μg+50 μg/1 g: tubes 15 g, 30 g or 60 g
Indications for use Daivobet
Chronic vulgar plaque psoriasis.
Psoriasis of the scalp, psoriasis of light and moderate severity of other parts of the body.
Pharmacological effect Daivobet
Combined medicinal agent for external use.
Calcipotriol is a synthetic analogue of the active metabolite of vitamin D. It causes inhibition of keratinocyte proliferation and accelerates their morphological differentiation.
Betamethasone - GKS for outdoor use, has local anti-inflammatory, antipruritic, vasoconstrictor and immunosuppressive effects, however, the exact mechanisms of anti-inflammatory action of topical steroids are not completely clear.
Pharmaco-therapeutic group
Antipsoriatic agents, antipsoriatic agents for external use, other antipsoriatic agents for external use
Clinical-pharmacological group
Preparation with antiproliferative and anti-inflammatory action for the treatment of psoriasis
Method of use and doses Daivobet
Outside. Adults are applied to the affected skin areas once a day.
The maximum daily dose is not more than 15 g, the maximum weekly dose is 100 g.
The conformity of indications and the dosage form used should be strictly observed.
