Instructions for Dexalgin (Dexketoprofen) 25 mg ampoules
English product name
Dexalgin®
Release form
25 mg/1 ml r/w and v/m injection:
amp. 2 ml 1, 5 or 10 pcs
Description Dexalgin:
The solution for in/in and in/m injection is transparent, colorless, with a characteristic alcohol odor.
1 ml 1 amp
- dexamoprofen trometamol 36.9 mg 73.8 mg,
- which corresponds to the content of dexamoprofen 25 mg 50 mg
- Auxiliary substances:
- ethanol 96% - 200 mg,
- sodium chloride - 8 mg,
- sodium hydroxide - up to pH 7.4,
- water d/i - up to 2 ml.
ATC codes
M01AE17 Dexketoprofen
Clinical-pharmacological groups / Group affiliation
NAPS
Active substance
decketoprofen
Pharmacotherapy group Dexalgin:
NSAIDs
Storage Conditions
The drug should be stored in a place inaccessible to children, protected from light at a temperature not higher than 25 ° C.
Best before date
Shelf life is 5 years. Use only transparent and colorless solutions.
After dilution, the solution is stored for 24 hours at a temperature of 2° to 8°C in a place protected from light.
Testimony Dexalgin:
The treatment of pain syndrome of various origins (including post-operative pain, bone metastasis pain, post-traumatic pain, kidney colic pain, algodismenorrhea, scialgia, radiculitis, neuralgia, toothache);
symptomatic treatment of acute and chronic inflammatory, inflammatory, degenerative and metabolic diseases of the musculoskeletal system (including rheumatoid arthritis, spondyloarthritis, arthrosis, osteochondrosis).
Method of use, course and dosage:
Dexalgin® is designed for inside venno and inside muscular insertion.
Recommended dose for adults: fifty mg every 8-12 hours. If necessary, it may be readministered at a 6-hour interval. The daily dose is 150 mg.
In older patients and patients with liver and/or kidney dysfunction, Dexamgin® should be administered at lower doses; The daily dose is fifty mg.
Dexalgin® is intended for short-term (no more than two days) use in the period of acute pain syndrome. In the future it is possible to transfer the patient to analgesics for admission.
Rules of preparation and introduction of solutions
The contents of one ampoule (two ml) are slowly introduced deep into/m.
The contents of one ampoule (two ml) are administered by a slow in/in injection lasting at least 15 seconds.
The contents of one ampoule (two ml) are diluted into thirty to one hundred ml of a physiological solution, a glucose solution or a Ringer solution (lactate). The solution should be prepared under aseptic conditions and always protected from daylight exposure. The diluted solution (to be transparent) is introduced by a slow in/in infusion of ten to thirty minutes.
Application in elderly patients
Caution should be used in patients of older age (over 65 years).
Use in children
Contraindication: child's age.
- Nosology Dexketoprofen (ICD codes)
- K08.8
- Other refined changes of teeth and their support apparatus (including toothache)
- M05
- Seropositive rheumatoid arthritis
- M15
- Polyarthrosis
- M42
- Spinal osteochondrosis
- M45
- Ankylosing spondylitis
- M46
- Other inflammatory spondylopathies
- M54.1
- Radikulopathy
- M54.3
- Ishias
- M54.4
- Lumbago with Sciatica
- M79.2
- Neuralgia and Neuritis Unspecified
- N23
- Renal colic unspecified
- N94.4
- Primary dysmenorrhea
- N94.5
- Secondary dysmenorrhea
- R52.0
- Acute pain
- R52.2
- Other persistent pain (chronic)
- T14.3
- Dislocation, stretching and overtension of the capsule-bonding apparatus of the unspecified body region joint
Pharmacological effect Dexketoprofen:
Nonsteroidal anti-inflammatory drug Dexalgin (NSAIDs). It has analgesic, anti-inflammatory and antipyretic effects. The mechanism of action is associated with inhibition of prostaglandin synthesis at COX-1 and COX-2 levels.
The analgesic effect occurs thirty minutes after parenteral administration. The duration of the analgesic effect after administration in a dose of fifty mg is four to eight hours
In combination therapy with opioid analgesics of dexamoprofen, tromethamol significantly (up to 30-45%) reduces the need for opioids.
