Diaflex Rompharm (Diacerein) 50 mg 30 capsules

Diaflex Rompharm (Diacerein) 50 mg 30 capsules

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Diaflex Rompharm (Diacerein) used for inflammatory and inflammatory-dystrophic diseases of the musculoskeletal system
Active substance:Diacerein
Pharmacological group:Musculoskeletal system
Dosage mg:50
Pills in 1 package:30
In stock
$40
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Instructions for Diaflex Rompharm (Diacerein) 50 mg 30 capsules

Diaflex Rompharm (Diacerein) 50 mg 30 capsules

English product name
Diaflex Rompharm

Release form
Capsules

Description Diaflex Rompharm:

Capsules are solid gelatine, size №1, yellow with a weak brown tint; The capsule contents are yellow powder.

1 cap.
Diacerein 50 mg
Auxiliary substances: magnesium stearate - 12.5 mg, lactose monohydrate (capsule 60) - up to 250 mg.

Capsule composition Diaflex Rompharm:
titanium dioxide - 0.75 mg,
iron oxide yellow - 2.2125 mg,
gelatin - up to 75 mg.

10 pcs - box-type contour (3) packages - cardboard packs.

ATC codes
M01AX21 Diacerein

Clinical-pharmacological groups / Group affiliation
NAPS

Active substance
Diacerein

Pharmacotherapy group:

NSAIDs

Storage Conditions
The drug Diacerein should be stored in a place protected from light, inaccessible to children at a temperature not higher than 25 ° C.

Best before date
The shelf life is three years.

Testimony Diaflex Rompharm:

symptomatic treatment of osteoarthrosis of hip and knee joints.

Method of use, course and dosage Diaflex Rompharm:

The drug Diacerein is taken inside, during meals. The capsule must be swallowed whole, not chewed, washed with enough water.
Prescribe the drug should be a specialist with experience in the treatment of osteoarthrosis.
It is recommended to start the treatment with one capsule (50 mg)/day during the meal (for example, dinner) for 4 weeks, because during the first two weeks of use the drug can cause acceleration of the transit of the contents of the intestines.

The dose is then increased to 100 mg day - one capsule (50 mg) twice/day (morning and evening).
Treatment is carried out continuously for a long time or for courses of at least four months.
In patients with moderate-severity renal failure (CC 30-60 ml/min), the dose should be reduced to fifty mg/day.

Use in liver disorders
The use of the preparation is contraindicated in cases of liver diseases, including anamnesis.

Terms of Sale
The drug Diacerein is prescription.

Application in elderly patients
Patients over the age of 65 should be given the drug with caution.

Use in children
The use of the preparation in the age of up to 18 years is contraindicated.

  • Nosology Diacerein (ICD codes)
  • M16
  • Coxarthrosis [hip arthrosis]
  • M17
  • Gonarthrosis [knee arthrosis]

Pharmacological effect Diaflex Rompharm:

Diacerein is a derivative of anthraquinoline, a diacetylated derivative of reine. Metabolizing to an active metabolite, reine, inhibits interleukin-1 activity, which plays an important role in the development of inflammation and cartilage degradation in osteoarthrosis.

Diacerein inhibits the action of other cytokines causing inflammation, including interleukin-6, FNO-α. It slows down the synthesis of metalloproteinases (collagenases, elastases) that contribute to the damage of cartilage tissue. When used for a long time, Diacerein stimulates the synthesis of proteoglycans and does not affect the synthesis of prostaglandins.
The preparation exhibits analgesic and anti-inflammatory activity during oral administration. The action takes two to four weeks.

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