Instructions for Dorithricin (Tyrothricin, Benzalkonium chloride, Benzocaine) 10 tablets
English product name
Dorithricin
Release form
Dipping tablets
Description:
The tablets are round, flat-cylindrical, chamfered, with Dorithricin marking on one side, white with a mint smell.
1 tab.
benzalkonium chloride 1 mg
benzocaine 1.5 mg
tyrotricin 0.5 mg
Auxiliary substances: sorbitol - 871 mg, talc - 80 mg, povidone (polyvidon K25) - 10 mg, sodium carmellose - 10 mg, sugar stearate - 20 mg, peppermint leaf oil - 5 mg, sodium saccharinate - 1 mg.
10 pcs - blister packs (1) - cardboard packs.
ATC codes
R02AA20 Other drugs
Clinical-pharmacological groups / Group affiliation
Preparation with antimicrobial and local anesthetic effect for local use in ENT practice and dentistry
Active substance
benzalkonium chloride
benzocaine
tyrotricin
Pharmacotherapy group Dorithricin:
Antiseptic + local anesthetic
Storage Conditions
At room temperature not higher than 25°C in a dry, light-proof place.
Best before date
Shelf life is 5 years.
Testimony Dorithricin:
- Infectious inflammatory diseases of the oral cavity and throat, accompanied by pain syndrome:
- pharyngitis,
- laryngitis,
- the beginning stage of angina;
- Inflammation of the gums and mucous membranes of the mouth (gingivitis, stomatitis).
Method of use, course and dosage Dorithricin:
Inside. For adults and children over 6 years of age, slowly spread 1 pill every 3 hours in the oral cavity. The maximum daily dose is 6 tablets. Treatment course 7 days. Increase the course of therapy if necessary - on the recommendation of the doctor.
Use in children
It is contraindicated to children under 6 years of age.
- Nosology (ICD codes)
- J02
- Acute pharyngitis
- J03
- Acute tonsillitis
- J04
- Acute laryngitis and tracheitis
- J31
- Chronic rhinitis, nasopharyngitis and pharyngitis
- J35.0
- Chronic tonsillitis
- J37
- Chronic laryngitis and laryngotracheitis
- K05
- Gingivitis and periodontal diseases
- K12
Pharmacological effect Dorithricin:
A complex preparation, the action of which is conditioned by its constituent components.
Benzocaine is a local anesthetic that reduces the pain of swallowing, which often accompanies the infection-inflammatory processes of the mouth and throat.
Benzalkonium chloride is a quaternary ammonium compound, is related to cationic surfactants, interacts with lipoproteins and impairs permeability of cell membranes. It has antiseptic properties, is active against Gram-positive bacteria, has fungicidal effect on Candida albicans and some lipophilic viruses.
Thyrotricin, a topical antibiotic, is a mixture of antimicrobial linear and cyclic polypeptides isolated at the fermentation stage of Brevibacillus brevis Dudos, consisting primarily of gramicidin and tyrocydine. Tyrotricin acts bactericidically, causing the breakdown of phosphorylation processes in the cellular respiration chain and destroying bacterial cell membranes. Due to the specific mechanism of action of tyrotricin, which is absent in systemic antibiotics, cross resistance to the drug does not arise.