Instructions for Exhole (Ursodeoxycholic acid)
English Product Name
Exhol
Dosage form
tab. chris. film shell 500 mg: 10, 30, 50 or 100 pcs.
Description:
Tablets,
film-coated white or almost white,
oval,
with risk;
on the cross-section - white or almost white.
1 tab.
ursodeoxycholic acid 500 mg
Excipients: calcium hydrogen phosphate dihydrate - 40 mg,
calcium stearate - 7 mg,
sodium carboxymethyl starch - 28 mg,
potato starch - 33.5 mg,
mannitol - 58 mg,
macrogol (polyethylene glycol 4000) - 3.5 mg,
povidone K30 - 30 mg.
Composition of the film shell:
opadrai white - 20 mg (hypromellose (hydroxypropyl methylcellulose) - 6.75,
hyprolose (hydroxypropyl cellulose) - 6.75,
talc - 4 mg,
titanium dioxide - 2.5 mg).
Pharmachologic effect Exhole:
Hepatoprotective agent also has a choleretic, cholelitholytic,
lipid-lowering, hypocholesterolemic and some immunomodulatory effect.
With high polar properties, ursodeoxycholic acid (UDCA) forms non-toxic mixed micelles with apolar (toxic) bile acids, which reduces the ability of gastric reflux to damage cell membranes in biliary reflux gastritis and reflux esophagitis
Testimony Exhole:
- dissolution of small and medium cholesterol stones with a functioning gallbladder;
- biliary reflux gastritis;
- primary biliary cirrhosis of the liver in the absence of signs of decompensation (symptomatic treatment);
- chronic hepatitis of various genesis;
- primary sclerosing cholangitis;
- cystic fibrosis (cystic fibrosis);
- non-alcoholic steatohepatitis;
- alcoholic liver disease;
- dyskinesia of the biliary tract.
Dosage, Course and Dosage Exhole:
Inside, without chewing, washed down with enough water.
Dissolution of cholesterol gallstones
The recommended dose of exchol® is ten mg / kg body weight per day.
The entire daily dose is taken once at night. The course of treatment is six to twelve months. To prevent the re-formation of stones, it is recommended to take the drug for several months after the stones are dissolved.
annoyance, course and annoy inside, whiteout shuing, gone down whit enouh wäter. Dissolution of Sholsterol Gollstones te recommended dose of exol® is tenge mg /kg body waite per de. te entyr daily dose isen onse at night. those courses of the third is sis to tuelv monts. then prevent te re-formation of stones, it is recommended to take those friends for several mts afterte stones are dissolutioned.
Use in children
Contraindicated use of the drug in children weighing up to 34 kg and under the age of 3 years.
Children older than 3 years of ursodeoxycholic acid are prescribed individually, at the rate of 10-20 mg / kg / day.
- Nosology (ICD codes)
- B18
- Chronic viral hepatitis
- E84
- Cystic fibrosis
- K29.9
- Gastroduodenitis unspecified
- K70
- Alcoholic liver disease
- K73
- Chronic hepatitis not classified under other headings
- K74.3
- Primary biliary cirrhosis
- K76.0
- Fatty liver (liver degeneration), not classified under other headings
- K80
- Cholelithiasis [cholelithiasis] (including hepatic colic)
- K82.8
- Other advanced diseases of the gallbladder and cystic duct (including dyskinesia)
- K83.0
- Cholangitis
