Instructions for Exoderil (Naftifine) cream 1%
English product name
Exoderil®
Release form
cream d/outer approx. 10 mg/1 g: 15 g or 30 g tubes
Description:
Cream for external application of white color, uniform or slightly grainy, shiny, with a weak characteristic smell.
1g
naphtiphine hydrochloride 10.0 mg
Auxiliary substances: sodium hydroxide - 1.2 mg, benzyl alcohol - 10.0 mg, sorbitana stearate - 19.0 mg, cetilpalmitate - 20.0 mg, cetyl alcohol - 40.0 mg, stearyl alcohol - 40.0 mg, polysorbate 60 - 61.0 mg, isopropyl myristat - 80.0 mg, water purified - 718.8 mg.
ATC codes
D01AE22 Naftifine
Clinical-pharmacological groups / Group affiliation
Antifungal preparation for external use
Active substance Naftifine
naphtiphine hydrochloride
Pharmacotherapy group
Antifungal agent
Testimony Exoderil:
- Onychomycosis,
- bran lychee,
- epidermophytia of large skin folds and feet,
- rubromycosis,
- trichofitia,
- microsporia,
- candidiasis of skin,
- mycosis with secondary bacterial infection.
Method of use, course and dosage Exoderil:
It is used externally.
The dosing regime is set individually, depending on the indications Naftifine and the dosage form used.
Special Instructions Naftifine
To achieve therapeutic effect, course treatment is required.
Use in children
Not recommended for use in children (experience of clinical use is limited).
- Nosology Exoderil (ICD codes)
- B35.1
- Nail mycosis
- B35.2
- Mikoz brushes
- B35.3
- Mycosis stop
- B35.4
- Torso mycosis
- B35.6
- Epidermofitia
- B35.8
- Other dermatophytes
- B36.0
- Multicolored fox
- B37.2
- Skin and nail candidiasis
Pharmacological effect Exoderil:
An antifungal agent for external use relates to allylamines. The mechanism of action is associated with inhibition of squalene-2,3-epoxidase, which leads to a reduction in the formation of ergosterol, which is part of the cell wall of the fungus.
It is active against dermatophytes such as Trichophyton, Epidermophyton, Microsporum, Aspergillus spp., Candida spp., Pityrosporum, and other fungi such as Sporothrix schenckii.
For dermatophytes and aspergillus, naphtiphin acts fungicidally.
For yeast fungi, naphtiphin exhibits fungicidal or fungistatic activity depending on the strain of the microorganism.
It has antibacterial activity against gram-positive and gram-negative microorganisms, which can cause secondary bacterial infections.
It has an anti-inflammatory effect that contributes to the rapid disappearance of symptoms of inflammation, especially itching.
