Instructions for Exoderil (Naftifine) solution 1%
English product name
Exoderil®
Release form
Average: 1% fl 10 ml, 20 ml or 30 ml with drip plug
Description Exoderil:
The solution Exoderil for external use is transparent, colorless or slightly yellow, with the smell of ethanol.
1 ml
naphtiphine hydrochloride 10 mg
Auxiliary substances: propylene glycol - 50 mg, ethanol - 400 mg, water purified - 475 mg.
10 ml - bottles of dark glass with a drip plug with a plastic screwing cover with the control of the first opening or with polyethylene/polypropylene cap-drip (1) - packs of cardboard.
20 ml - bottles of dark glass with a drip-drip plug with a plastic screwing cover with the control of the first opening or with polyethylene/polypropylene cap-drip (1) - packs of cardboard.
30 ml bottles of dark glass with a drip-plug with a plastic screwing cover with the control of the first opening or with a polyethylene/polypropylene cap-drip (1) - packs of cardboard.
ATC codes
D01AE22 Naftifine
Clinical-pharmacological groups / Group affiliation
Antifungal preparation for external use
Active substance
naphtiphine hydrochloride
Pharmacotherapy group
Antifungal agent
Testimony Naftifine:
- Onychomycosis,
- bran lychee,
- epidermophytia of large skin folds and feet,
- rubromycosis,
- trichofitia,
- microsporia,
- candidiasis of skin,
- mycosis with secondary bacterial infection.
Method of use, course and dosage of the preparation:
It is used externally. The dosing regime is set individually, depending on the indications and the dosage form used.
Special Instructions Naftifine
To achieve therapeutic effect, course treatment is required.
Use in children
Not recommended for use in children (experience of clinical use is limited).
Nosology Naftifine (ICD codes)
B35.1
Nail mycosis
B35.2
Mikoz brushes
B35.3
Mycosis stop
B35.4
Torso mycosis
B35.6
Epidermofitia
B35.8
Other dermatophytes
B36.0
Multicolored fox
B37.2
Skin and nail candidiasis
Pharmacological effect Naftifine:
An antifungal agent for external use relates to allylamines. The mechanism of action is associated with inhibition of squalene-2,3-epoxidase, which leads to a reduction in the formation of ergosterol, which is part of the cell wall of the fungus.
It is active against dermatophytes such as Trichophyton, Epidermophyton, Microsporum, Aspergillus spp., Candida spp., Pityrosporum, and other fungi such as Sporothrix schenckii.
For dermatophytes and aspergillus, naphtiphin acts fungicidally.
For yeast fungi, naphtiphin exhibits fungicidal or fungistatic activity depending on the strain of the microorganism.
It has antibacterial activity against gram-positive and gram-negative microorganisms, which can cause secondary bacterial infections.
It has an anti-inflammatory effect that contributes to the rapid disappearance of symptoms of inflammation, especially itching.
