Instructions for Ferrum
Excipients
sucrose, sorbitol (solution), methyl parahydroxybenzoate
propyl parahydroxybenzoate
ethanol
cream flavor
sodium hydroxide
water.
100 ml - dark glass bottles complete with a measuring spoon - cardboard packs.
(Oral iron (ferric) preparations)
Ferrum
Clinical and pharmacological groups Ferrum Lek:
Antianemic drug
Active substance Ferrum Lek:
iron [III] hydroxide polymaltose
Pharmaco-therapeutic group Ferrum Lek:
Hematopoiesis stimulant-iron drug
pharmachologic effect Ferrum Lek:
A remedy for the treatment of anemia. The multinuclear centers of Fe3 + hydroxide are surrounded on the outside by many non-covalently bound polymaltose molecules, forming a complex with a total molecular weight of 50 thousand Daltons, which is so large that its diffusion through the intestinal mucosa membranes is approximately 40 times less than that of Fe2 + hexahydrate.
This macromolecular complex is stable, does not release in the form of free ions, and is similar in structure to the natural compound of iron and ferritin. Due to this similarity, Fe3 + ions from the intestine enter the blood only through active absorption, which explains the impossibility of overdose (and intoxication), in contrast to simple iron salts, the absorption of which occurs along a concentration gradient.
The absorbed iron is deposited in a form associated with ferritin, mainly in the liver. Later, in the bone marrow, it is incorporated into hemoglobin. Iron, which is part of the Fe3 + hydroxide of the polymaltose complex, does not possess prooxidant properties (which are inherent in simple Fe2 + salts), which leads to a decrease in the oxidation of LDL and VLDL.
Quickly replenishes iron deficiency in the body, stimulates erythropoiesis, restores hemoglobin.Ferrum
Indications Ferrum Lek:
For oral administration: treatment of iron deficiency anemia of various origins and latent iron deficiency in infants and young children; increased need for iron (pregnancy, lactation, donation, period of intensive growth, vegetarianism, old age).
For parenteral administration: treatment of deficiency anemia with ineffectiveness or impossibility of taking oral iron-containing drugs (including in patients with gastrointestinal diseases, with malabsorption syndrome).
Method of application Ferrum:
For oral administration and intramuscular administration.
The dose is set individually, depending on the indications, the patient's age and the clinical situation.
Drug interactions Ferrum Lek:
Oral forms
no interactions with other drugs Ferrum were found.
Solution for injection:
ACE inhibitors enhance systemic effects.
Should not be used concurrently
Application during pregnancy and lactation Ferrum Lek:
No negative effect on the fetus has been established when using oral forms during pregnancy (including in the first trimester).
IM administration is contraindicated in the first trimester of pregnancy.
In small quantities, unchanged iron from the polymaltose complex can be excreted in breast milk, however, adverse effects are unlikely to occur in breastfed babies.
Side effect Ferrum Lek:
Ingestion : dyspepsia (feeling of fullness and pressure in the epigastric region, nausea, constipation or diarrhea), dark color of feces (due to the excretion of non-absorbed iron and has no clinical significance).
With i / m administration : in rare cases - arthralgia, swollen lymph nodes, fever, headache, malaise, dyspepsia (nausea, vomiting); extremely rarely - allergic reactions. Local reactions (with the wrong injection technique): skin staining, pain, inflammation.
Contraindications for use Ferrum Lek:
Excess in the body (hemochromatosis, hemosiderosis); anemia not associated with iron deficiency (hemolytic anemia or megaloblastic anemia caused by a lack of cyanocobalamin, aplastic anemia); violation of the mechanisms of iron utilization (lead anemia, sideroachrestic anemia, thalassemia, tardive porphyria of the skin); hypersensitivity to the active substance.
For IM administration only (optional): Randu-Weber-Osler disease; chronic polyarthritis; acute infectious kidney disease; uncontrolled hyperparathyroidism; decompensated cirrhosis of the liver; infectious hepatitis; children under the age of 4 months; I trimester of pregnancy.
Application in children Ferrum Lek:
Use in children under 4 months of age is contraindicated.
Nosology (ICD codes)
Iron-deficiency anemia
Iron deficiency
Anemia complicating pregnancy, childbirth and the puerperium
Ferrum