Instructions for Gepon Lyophilisat (immunomodulator) lyophilisate for solution preparation 2 mg
English product name
Gepon
Release form
p-r d/ingestion and external approx 0.02%: fl 10ml
p-r d/ingestion and external approx. 0.1%: fl 1 ml
p-r d/ingestion and external approx. 0.1%: fl 2 ml
p-r d/ingestion and external approx 0.02%: fl 5 ml
lyof powder d/r-ra ingestion and external approx. 1 mg: fl
lyof powder d/r-ra ingestion and external approx. 1 mg: amp.
lyof powder r-ra d/ingestion and external approx. 2 mg: fl
lyof powder r-ra d/ingestion and external approx. 2 mg: amp.
Description Gepon
0.02% Intake and Outdoor Solution 1 ml 1 fl
synthetic peptide consisting of 14 amino acid residues 200μg 2 mg
10 ml - bottles (1), complete with drip lid or with spray nozzle or with pipette or with syringe - cardboard packs.
ATC codes
L03AX Other immunostimulators
Clinical-pharmacological groups / Group affiliation
Immunostimulating preparation
Active substance
synthetic peptide consisting of 14 amino acid residues
Pharmacotherapy group Gepon
Immunomodulatory agent
Storage Conditions
List B. The drug should be stored in a dry, protected from light at a temperature not higher than 8 ° C. Storage period - 2 years.
Testimony Gepon
correction of weakened immunity in immunodeficiency states;
HIV treatment;
Increasing immune defenses against infections
Treatment and prevention of opportunistic infections caused by bacteria, viruses or fungi
Treatment and prophylaxis of candidiasis of skin and mucous membranes (including due to antibiotic therapy);
reduction of inflammation (redness, swelling, itching, burning, pain) of mucous membranes and skin, as well as dryness of mucous membranes.
Method of use, course and dosage Gepon
The preparation is administered to adults and children over 12 years of age at a dose of 10 mg per oral dose of 1 times/day, or 1-2 mg as a 0.02-0.04% solution for local treatment of mucous membranes and skin 1 time/day.
For the treatment of opportunistic infections in HIV infection or other immunocompromised conditions, Hepon is prescribed 10 mg daily per oral dose for 1-3 months.
For the treatment and prophylaxis of infections of mucous membranes and skin caused by Candida fungi, local application of Hepon (0.02-0.04% solution) in the form of irrigation of affected areas of mucous membranes and skin is recommended. Treatment course - 3 irrigation with an interval of 1-3 days between treatments.
In the case of candidiasis vulvovaginite, urethrite and cervicite, 0.02-0.04% irrigation with a solution of Hepon of the mucous membrane of the vulva, vagina, cervix is used in women, as well as primoges on affected skin areas adjacent to the entrance to the vagina.
For candidiasis urethritis, balanoposthite in men, the intillations of 0.02-0.04% of Hepon solution into urethra and primochki to the affected skin areas are used.
For the prophylaxis of candidiasis of mucous membranes and skin as a possible complication in the case of intensive antibiotic therapy, it is required to carry out irrigation or primochki of 0.02-0.04% with a Hepon solution during the course of antibiotic treatment.
To reduce the intensity of inflammation, the mucous membranes should be irrigated with 0.02-0.04% Hepon solution, and gauze wipes soaked with 0.02-0.04% Hepon solution should be applied to inflamed skin areas.
Rules of solution preparation
Before use, the powder should be dissolved in 5 ml of water for injection or saline solution.
Use in children Gepon
The drug is contraindicated in children under six years of age.
- Nosology (ICD codes)
- B24
- Human immunodeficiency virus [HIV], unspecified
- B37.0
- Candidiasis stomatitis
- B37.2
- Skin and nail candidiasis
- B37.3
- Candidiasis vulva and vagina
- B37.4
- Candidiasis of other urogenital localizations
- D84.9
- Immunodeficiency unspecified
Pharmacological effect Gepon
Immunomodulating preparation. It has an antiviral effect. The preparation induces α- and β-interferons, mobilizes and activates macrophages, limits the production of cytokines of inflammation (interleukin 1, 6, 8 and the tumor necrosis factor), stimulates the production of antibodies to various antigens of an infectious nature, suppresses the replication of viruses, increases the resistance of the body to infections caused by viruses, bacteria or fungi.
In HIV patients, Hepon reduces HIV concentration in blood cells and plasma, while activating HIV-specific immune responses. In most HIV-infected patients, CD4+ T- and NK-cells increase in content, neutrophils and CD8+ T-cells increase functional activity, which are key elements of the body's defense against bacteria, viruses and fungi, antibodies specific to HIV antigens and antigens of opportunistic infections pathogens increase.