Instructions for Macmiror Complex (Nystatin, Nifuratel)
Release form:
vaginal supp. 500 mg + 200 thousand IU: 8 or 12 pcs
Vaginal liquid cream
Description Nystatin:
Rectal suppositories are a highly-effective photoactive product intended to restore and stimulate regeneration in tissues in scope of photodynamic therapy. The contents of the suppositories are a yellow oil slurry.
1 sp.
Nifuratel 500 mg
Nystatin 200,000 ME
Auxiliary substances: dimethylpolysiloxane AK 1000 (dimethicone) 960.0 mg.
Shell Composition: gelatin 351.0 mg, glycerol 171.0 mg, ethylparahydroxybenzoate sodium 1.8 mg, propyl parahydroxybenzoate sodium 1.0 mg, titanium dioxide 0.4 mg, iron oxide yellow 2.4 mg
ATC codes
G01AX Other antiseptics and antimicrobials for the treatment of gynaecological diseases
Clinical-pharmacological groups / Group affiliation
Antibacterial, antibacterial and antifungal agent for topical use in gynaecology
Active substance
nystatin
Nifuratel
Pharmacotherapy group:
Antimicrobial combined agent (antimicrobial and antiskid agent+antifungal agent)
Pharmacological effect:
Macmyror complex 500 - antimicrobial preparation for local use. It has antiplatozoic, antifungal and antibacterial effects.
active substance Nifuratel, a derivative of nitrofuran. It is highly active against a number of bacteria, fungi and protozoa (including Trichomonas vaginalis).
Nystatin is an antifungal antibiotic of the group of polyenes. By binding to sterols in the cell membrane of fungi, it disrupts its permeability, leading to cell death. It is highly active in the genus Candida albicans.
The combination of the active substance nifuratel and nystatin makes it possible to achieve a more pronounced antifungal action and to significantly extend the spectrum of antimicrobial action.
The high effectiveness and low toxicity of the components of the preparation make it possible to use the preparation in a wide range of clinical applications in the treatment of mixed-etiology vaginitis, in particular for the prophylaxis of mycosis caused by the specific treatment of trichomoniasis.
The McMiroir complex does not disturb the physiological flora, which allows to avoid the development of dysbacteriosis and quickly restore the norm of the vagina.
Testimony Nystatin:
Vulvovaginal infections caused by drug-sensitive pathogens: including bacterial vaginitis, vaginal trichomoniasis; vaginitis, caused by fungi of the genus Candida, mixed vaginitis.
Method of use, course and dosage:
Intravaginally. The frequency of use depends on the dosage form used.
It can be applied within 8 days or according to the doctor's recommendations. If necessary, treatment can be repeated after menstruation.
Use in pregnancy and breastfeeding
The use of the drug Nifuratel in pregnancy is possible if the potential benefit to the mother exceeds the risk to the fetus or child.
It can be used during breastfeeding, because the drug is practically not absorbed through the mucosae, so it does not penetrate into breast milk.
Side Effect:
Possible: allergic reactions in the form of skin rashes or itching. In the development of allergic reactions, use should be stopped.
Contraindications for use Nifuratel:
Child age (for use in the form of suppositories); increased sensitivity to the components of the combined drug.
Special Instructions Nystatin
The sexual partner must be treated at the same time because of the risk of re-infection. Sexual contact should be avoided during treatment.
Use in children
It is not used in the form of suppositories.
Nosology (ICD codes)
A59
Trichomoniasis
B37.3
Candidiasis vulva and vagina
N76
Other inflammatory diseases of the vagina and vulva
N77.1
Vaginitis, vulvite and vulvovaginitis for infectious and parasitic diseases classified in other headings
