Instructions for Maruxa (Memantine) tablet
English product name
Maruxa
Release Form
tab. film sheath, 10 mg: 30 or 60 pcs.
Description Maruxa
The tablets are covered with a film shell of white color, oval, double-convex, with a risk on one side; the view on the fracture is an uneven surface of white color.
1 tab.
memantina hydrochloride 10 mg
Auxiliary substances: lactose monohydrate 51.45 mg, cellulose microcrystalline 175 mg, silicon dioxide colloid 2.5 mg, talc 9.8 mg, magnesium stearate 1.25 mg.
The film sheath contains: methacrylic acid and ethylacrylate copolymer (1:1), 30% aqueous dispersion, 0.6 mg (in conversion to dry matter; also contains sodium lauryl sulfate and polysorbate-80 as emulsifiers), talc 0.27 mg, triacetine 0.12 mg, cimeticon 0.01 mg.
10 pcs. - box-type contoured packages (PVC/PVC/aluminium foil) (3) - cardboard packages.
10 pcs. - box-type contoured packages (PVC/PVC/aluminium foil) (6) - cardboard packages.
ATC codes
N06DX01 Memantine
Clinical-pharmacological groups / Group affiliation
Glutamate blocker of NMDA receptors. Preparation for the treatment of dementia
Active substance
memantina hydrochloride
Pharmaco-therapeutic group Maruxa
Dementia Treatment Tool
Pharmacological effect Maruxa
Agent for treating dementia. It is a non-competitive antagonist of glutamate NMDA receptors (including in the black substance), and therefore reduces the overstimulating effect of cortical glutamate neurons on neostriatum, which develops amid insufficient dopamine release. By reducing the supply of Ca2+ to neurons, it reduces the possibility of their destruction.
It has nootropic, cerebrovasodilating, antihypoxic and psychostimulatory effects.
Improves memory weakness, increases concentration ability, reduces fatigue and depression symptoms, and decreases skeletal muscle spasticity caused by brain disease or damage.
Testimony Maruxa
Moderate to severe dementia in Alzheimer's disease.
Method of use, course and dosage
When ingested, the initial dose for adults is 5 mg/day. The dose can be increased weekly by five mg. The average maintenance dose is ten to twenty mg/day. The maximum dose is twenty mg/day.
- Nosology (ICD codes)
- F00
- Dementia in Alzheimer's
