Instructions for Milurite (Allopurinol) pills
English Product Name
Milurit
Dosage form
tab. 100 mg: 50 pcs
Description Milurite:
Tablets of white or grayish-white color, round, flat, with a chamfer, with a risk on one side and engraved "E351" - on the other, without or almost odorless.
1 tab.
allopurinol 100 mg
Excipients: lactose monohydrate - 50 mg, potato starch - 32 mg, povidone K25 - 6.5 mg, talc - 6 mg, magnesium stearate - 3 mg, sodium carboxymethyl starch (type A) - 2.5 mg.
50 pcs. - bottles of dark glass (1) - packs of cardboard.
ATX Codes
M04AA01 Allopurinol
Clinical and pharmacological groups / Group affiliation
A drug that affects the exchange of uric acid. Anti-gouty drug
Active ingredient
Allopurinol
Pharmaco-therapeutic group Milurite
Antigout, xanthine oxidase inhibitor
pharmachologic effect:
A tool that disrupts the synthesis of uric acid. It is a structural analogue of hypoxanthin. Inhibits the enzyme xanthine oxidase, which is involved in the conversion of hypoxanthin to xanthine and xanthine to uric acid.
Testimony:
- Treatment and prevention of gout and hyperuricemia of various genesis
- (including in combination with nephrolithiasis,
- renal failure, urate nephropathy).
- Recurrent mixed oxalate-calcium kidney stones in the presence of hyperuricosuria.
- Increased formation of urates due to enzyme disorders.
- Prevention of acute nephropathy in cytostatic and radiation therapy of tumors and leukemia, as well as in complete
- therapeutic fasting.
Dosage, Course and Dosage Milurite:
Install individually, under the control of the concentration of urates and uric acid in the blood and in the urine. Adults when taken orally - 100-900 mg per day, depending on the severity of the course of the disease. The frequency of admission is two to four times a day after meals. Children under the age of fifteen years - 10-20 mg / kg / day or one hundred-400 mg per day
Maximum doses: Milurite in case of impaired renal function (including those caused by urate nephropathy) - one hundred mg / day. An increase in the dose is possible in cases where, against the background of the therapy, an increased concentration of urates in the blood and urine persists.
Use in children Allopurinol
In children, it is used only for malignant neoplasms (especially leukemias), as well as for some enzyme disorders (Lesch-Nyhen syndrome).
The dosage regimen is set individually, under the control of the concentration of urates and uric acid in the blood and urine: children under the age of 15 years - 10-20 mg / kg / day or 100-400 mg / day.
- Nosology Milurite (ICD codes)
- E79
- Disorders of the exchange of purines and pyrimidines
- M10
- Gout
- N20
- Kidney and ureter stones
- N21
- Stones of the lower urinary tract
- Y43.1
- Antitumor antimetabolites
- Y43.2
- Natural antitumor drugs
- Y43.3
- Other anticancer drugs
- Y84.2
- Radiological procedure and radiation therapy
