indications for OTRIVIN
Description OTRIVIN:
Otrivin 0.1% "moisturizing formula" - a vasoconstrictor nasal spray for adults and children from 12 years old, containing 0.1% xylometazoline, is used for respiratory diseases with symptoms of rhinitis (runny nose):
Helps fight nasal congestion, thanks to the active ingredient - xylometazoline ...
The moisturizing formula helps to reduce the symptoms of irritation and dryness of the nasal mucosa.
Relieves congestion within 2 minutes after use, maintaining the effect for up to 12 hours.
Structure OTRIVIN:
Active ingredient: xylometazoline hydrochloride 1 mg. Excipients: sodium dihydrophosphate dihydrate 5 mg, sodium hydrogen phosphate dodecahydrate 1.7 mg, disodium edetate 0.5 mg, benzalkonium chloride 50% solution 0.1 mg (in terms of benzalkonium chloride 0.05 mg), sorbitol 70% 20 mg , hypromellose-4 thousand 5 mg, sodium chloride 4 mg, purified water up to 1 ml.
Indications for use OTRIVIN:
Acute respiratory diseases with symptoms of rhinitis (runny nose), acute allergic rhinitis, hay fever, sinusitis, eustachitis, otitis media (to reduce swelling of the nasopharyngeal mucosa). Preparing the patient for diagnostic manipulations in the nasal passages.
Pharmacokinetics OTRIVIN:
When applied topically in recommended dosages, it is practically not absorbed, plasma concentrations are below the detection limit.
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Pharmacodynamics OTRIVIN:
Xylometazoline belongs to the group of local vasoconstrictor agents (decongestants) with? -Adrenomimetic action, causes narrowing of the blood vessels of the nasal mucosa, eliminating edema and hyperemia of the nasopharyngeal mucosa. Xylometazoline also reduces concomitant mucus hypersecretion and facilitates drainage of blocked nasal passages, and thus improves nasal breathing in case of nasal congestion. Xylometazoline is well tolerated by patients with sensitive mucous membranes and does not interfere with mucus separation. Xylometazoline has a balanced pH value characteristic of the nasal cavity. The preparation contains inactive components - sorbitol and hypromellose (methylhydroxypropylcellulose), which are moisturizers. In this way,
The moisturizing formula can reduce the symptoms of irritation and dryness of the nasal mucosa caused by long-term use of xylometazoline. In therapeutic concentrations, the drug OTRIVIN does not irritate the mucous membrane, does not cause hyperemia. The effect occurs within 2 minutes after application and lasts for 12 hours (for example, throughout the night). In vitro studies have shown that xylometazoline inhibits the infectious activity of the human rhinovirus that causes the "cold". throughout the night). In vitro studies have shown that xylometazoline inhibits the infectious activity of the human rhinovirus that causes the "cold". throughout the night). In vitro studies have shown that xylometazoline inhibits the infectious activity of the human rhinovirus that causes the "cold".
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Contraindications OTRIVIN:
Hypersensitivity to xylometazoline and other components of the drug, arterial hypertension, tachycardia, severe atherosclerosis, glaucoma, dry rhinitis or atrophic rhinitis, hyperthyroidism, condition after transsphenoidal hypophysectomy, surgical interventions on the meninges (history), children under 12 years of age.
Side effects OTRIVIN:
From the immune system: Very rarely: hypersensitivity reactions (angioedema, rash, itching).
From the nervous system: Often: headache. Rarely: insomnia, depression (with prolonged use in high doses).
From the senses: Very rare: impaired clarity of visual perception.
From the side of the cardiovascular system: Rarely: palpitations, increased blood pressure; very rare: tachycardia, arrhythmia.
From the respiratory system: Often: irritation and / or dryness of the nasal mucosa, burning, tingling, sneezing, hypersecretion of the nasopharyngeal mucosa.
From the digestive system: Often: nausea. Rarely: vomiting.
Local reactions: Often: burning at the site of application.
If any of the side effects indicated in the instructions are aggravated, or you notice any other side effects that are not indicated in the instructions, inform your
doctor.
Method of preparation or use OTRIVIN:
Intranasally.
Adults and children over 12 years old: 1 injection in each nasal passage 3 times a day. Should not be used more than 3 times a day.
It is recommended that the last application be carried out immediately before bedtime.
