Rhinostop (Xylometazoline) drops
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Rhinostop (Xylometazoline) drops

SKU:930
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Active substance:xylometazoline
Pharmacological group:Rhinitis medicines
Formulation:drops
Country of origin:Russia
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$5
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Instructions for Rhinostop (Xylometazoline)

Pharmacological properties Rhinostop (Xylometazoline):

Rinostop is a combined preparation containing paracetamol , pseudoephedrine hydrochloride and chlorphenamine maleate. It has antipyretic, analgesic, vasoconstrictor, antihistamine, sedative, antitussive and bronchodilatory effect, eliminates the symptoms of colds.
Paracetamol - a non-narcotic analgesic, in addition to analgesic, has antipyretic and mild anti-inflammatory effect.
Pseudoephedrine is a sympathomimetic with a moderate effect on α 1 -adrenergic receptors, causes vasoconstriction, reduces swelling and hyperemia of the mucous membrane of the nasal cavity, nasopharynx, paranasal sinuses, local exudative manifestations.
Chlorphenamine is an H 1 receptor blocker . In addition to the antihistamine, it has an antiserotonin, mild anticholinergic, sedative effect, reduces the severity of allergic reactions mediated by the action of histamine, capillary permeability, narrows the vessels of the nasal mucosa, reduces local exudative manifestations, inhibits the symptoms of allergic rhinitis: sneezing, rhinorrhea, rhinorrhea. The onset of action is 20-30 minutes, the duration of action is 4-4.5 hours.

Indications Rhinostop (Xylometazoline):

Influenza and colds accompanied by fever
headache
rhinitis with swelling of the nasal mucosa
allergic rhinitis

Application Rhinostop (Xylometazoline):

Tablets: Adults and children over the age of 12 years: 1 tablet every 6 hours, for children aged 6-12 years - 1 / 2 t abletki every 6 hours Duration of application - no more than 3-5 days.
Syrup: children aged 2-5 years are prescribed 1 teaspoon every 12 hours, 6-12 years old - 2 teaspoons every 12 hours. Duration of use - no more than 3-5 days. Xylometazoline
In renal failure (creatinine clearance ≤10 ml / min), the interval between doses should be at least 8 hours.

Contraindications Rhinostop (Xylometazoline):

Hypersensitivity to the components of the drug Rhinostop, increased blood pressure and intraocular pressure, heart disease, peptic ulcer of the stomach or duodenum, simultaneous use of MAO inhibitors, children under the age of 6 years.

Side effects Rhinostop (Xylometazoline):

The side effects of paracetamol are usually mild. Violations of the digestive tract and allergic reactions in the form of skin rash, itching, Quincke's edema are possible; dry mouth, anemia, thrombocytopenia, agranulocytosis, hepatotoxic effect, hemolytic anemia , pancytopenia, nephrotoxic effect. Rhinostop
Pseudoephedrine can cause increased blood pressure, tachycardia, anxiety, and increased excitability.
Chlorphenamine sometimes causes drowsiness, anorexia, nausea, vomiting, diarrhea, or constipation.

Special instructions Rhinostop (Xylometazoline):

During the treatment period, the parameters of peripheral blood and the functional state of the liver are monitored.
The drug Rhinostop is prescribed with caution to persons with asthma, impaired liver and kidney function, hyperthyroidism, epilepsy, arrhythmia, glaucoma, obstruction of the bile ducts, impaired evacuation function of the stomach, benign prostatic hypertrophy, diabetes mellitus.
During the period of drug treatment, false results of laboratory tests are possible to determine the concentration of glucose and uric acid in the blood plasma.
During therapy, you should avoid drinking alcoholic beverages.
There is no experience of using the drug Rhinostop during pregnancy and lactation, so its appointment is possible only when the expected therapeutic effect for the mother outweighs the potential risk to the fetus or child.
During the period of use of the drug Xylometazoline, you should refrain from driving and working with potentially dangerous mechanisms.

Interactions Rhinostop (Xylometazoline):

Enhances the effects of MAO inhibitors, sedatives, ethanol. Ethanol enhances the sedative effect of chlorphenamine. Antidepressants, antiparkinsonian drugs, antipsychotics, phenothiazine derivatives increase the risk of side effects (urinary retention, dry mouth, constipation). GCS increase the risk of developing glaucoma. Paracetamol reduces the effectiveness of uricosuric drugs Rhinostop. Chlorphenamine, when taken simultaneously with MAO inhibitors, furazolidone, can lead to the development of a hypertensive crisis, agitation, hyperpyrexia. Tricyclic antidepressants enhance the sympathomimetic effect, the simultaneous use of halothaneincreases the risk of developing ventricular arrhythmias. Reduces the hypotensive effect of guanethidine, which in turn enhances the α-adrenomimetic effect of pseudoephedrine.

Overdose Rhinostop (Xylometazoline):

The first clinical symptoms of intoxication are nausea, vomiting, anorexia. Overdose leads to the development of seizures, hallucinations, fever, chills, dry mouth, skin hyperemia, mydriasis, tachycardia, increased blood pressure and arrhythmias, hepatotoxic action, in severe cases - up to liver necrosis.
In case of an overdose, it is necessary to take urgent measures within 4 hours. Induce vomiting or wash out the stomach. In the first 10 hours, N-acetylcysteine is used as an antidote to paracetamol . If necessary, prescribe anticonvulsants (diazepam IV slowly). Xylometazoline

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