Instructions for Papazol (Papaverine, Bendazole) 20 tablets
Release form:
tab 30 mg+30 mg: 10, 50 or 10,000 units
Description:
Tablets 1 tab.
papaverine hydrochloride 30 mg
bendazole hydrochloride 30 mg
10 pcs - package without pockets contour.
10 pcs - packages of box contour (1) - cardboard packs.
10 pcs - box-type contour (5) packages - cardboard packs.
10 pcs - packages without pockets contour (1) - cardboard packs.
10 pcs - packages of loop-free (5) - cardboard packages.
10 pcs - package without pockets contour (1000) - boxes cardboard.
10 pcs - box-type contouring packages (1000) - cardboard boxes.
ATC codes
A03AD51 Papaverine in combination with other drugs Papazol
Clinical-pharmacological groups / Group affiliation
Antihypertensive preparation
Miotropic spasmolytic
Active substance:
papaverine hydrochloride
bendazole hydrochloride
Pharmacotherapy group:
Spasmolytic agent
Pharmacological effect:
The combined preparation has spasmolytic, hypotensive and vasodilating effects.
Bendazol is a spasmolytic agent of myotropic action; it has hypotensive, vasodilating effect, stimulates function of spinal cord, has moderate immunostimulating activity.
Papaverine - spasmolytic agent, has a hypotensive effect. Inhibits phosphodiesterase, causes accumulation in the cell of cAMP and a decrease in calcium content, reduces tone and relaxes smooth muscles of internal organs (GI, respiratory and urogenital system) and vessels. In higher doses, it reduces cardiac muscle excitability and slows intra-cardiac conduction. The effect on the CNS is mild (in high doses it has a sedative effect).
Testimony:
Arterial hypertension (labile);
spasm of peripheral arteries and cerebral vessels;
spasm of smooth muscles of internal organs (including ulceration of stomach and duodenum, spasm of the gatekeeper, intestinal colic, cholecystitis, spastic colitis); polio (residual events);
peripheral facial nerve palsy.
Method of use, course and dosage:
Inside adults - 1-2 tab. 2-3 times/day.
Drug interaction:
The use of the preparation together with spasmolytics, sedative drugs Papazol, diuretics, tricyclic antidepressants, procainamide, reserpine and quinidine makes it possible to increase the degree of hypotensive effect.
Papazol weakens the action of anticholinesterase drugs Papazol on smooth musculature (galantamine, proserine, physiostigmin).
Adsorbents, astringent and enveloping drugs Papazol reduce the absorption of the preparation into the gastrointestinal tract.
Use in pregnancy and breastfeeding
It is administered with care during pregnancy and lactation.
Side Effect:
On the digestive side: nausea, constipation.
CNS: dizziness.
On the cardiovascular side: AV-blockade, arrhythmias, decreased myocardial contractility.
Others: allergic reactions, increased sweating.
Contraindications for use
AV conductivity violations; epileptic syndrome; Bronchoobstructive syndrome Children under 1 year of age; increased sensitivity to drug Papazol components.
It is used with caution in case of reduced intestinal peristalsis, head trauma, liver and/or kidney failure, hypothyroidism, adrenal insufficiency, prostate hyperplasia, pregnancy and lactation.
Special Instructions Papazol:
The safety of the drug Papazol during pregnancy and lactation is not established.
Application for kidney disorders
It is contraindicated in kidney failure.
Use in liver disorders
It is contraindicated in liver failure.
Use in children
It is contraindicated in children under 1 year of age.
Nosology (ICD codes) Papazol
B91
Polio's effects
G45
Transitory cerebral ischemic attacks [attacks] and related syndromes
G51
Facial nerve lesions
I10
Essential [primary] hypertension
I73.9
Peripheral vascular disease unspecified (including interspersed lameness, arterial spasm)
K25
Stomach ulcer
K26
Duodenum ulcer
K31.3
Pilorospasm not classified in other categories
K52.9
Non-infectious gastroenteritis and colitis unspecified
K81.0
Acute cholecystitis
K81.1
Chronic cholecystitis
R10.4
Other and unspecified abdominal pain (colic)
R51
Headache
