Instructions for Pariet (Rabeprazole) pills
English Product Name
Pariet®
Dosage form Pariet
tab., kr. enteric coating, 20 mg: 7 or 14 pcs.
Description Pariet:
Enteric-coated tablets of light yellow color, rounded shape, biconcave, on one side marked with red ink "E243"; on the transverse section - from white to almost white.
1 tab.
rabeprazole sodium 20 mg,
which corresponds to the content of rabeprazole 18.85 mg
Excipients:
mannitol (mannitol) - 40 mg, magnesium oxide - 63 mg,
hydroxypropyl cellulose weakly substituted (hyprolose) - 19.5 mg,
hydroxypropyl cellulose (hyprolose) - 3 mg,
magnesium stearate - 1.5 mg,
ethyl cellulose - 1 mg,
hypromellose phthalate - 12 mg,
diacetylated monoglyceride - 1.2 mg,
talc - 1.13 mg,
titanium oxide (E171) - 0.6 mg,
iron oxide yellow - 0.07 mg,
carnauba wax - 0.025 mg,
food red ink A1 (shellac white,
iron oxide red,
carnauba wax,
glyceric acid ester,
dehydrated ethanol,
1-butanol).
ATX Codes
A02BC04 Rabeprazole
Clinical and pharmacological groups / Group affiliation
Anti-ulcer drug Pariet
Active ingredient
rabeprazole sodium
Pharmaco-therapeutic group Pariet
Means of lowering the secretion of the glands of the stomach - proton pump inhibitor
pharmachologic effect Pariet:
Anti-ulcer agent, inhibitor of H + -K + -ATP-aza (proton pump). The mechanism of action is associated with the inhibition of the enzyme H + -K + -ATPase in the parietal cells of the stomach, which leads to blocking the final stage of the formation of hydrochloric acid. This action is dose-dependent and leads to inhibition of both basal and stimulated secretion of hydrochloric acid, regardless of the nature of the stimulus.
Testimony Pariet:
Peptic ulcer of the stomach and duodenum in the acute phase; gastric and duodenal ulcer associated with Helicobacter pylori (in combination with antibiotics); gastroesophageal reflux.
Dosage, Course and Dosage:
Inwards.
Use in case of impaired liver function
Patients with impaired liver function dose adjustment is not required, however, in patients with severe impairment of liver function, rabeprazole is recommended to be used with caution.
Use in children
Contraindicated in children and adolescents under the age of 18 years.
- Nosology (ICD codes)
- B98.0
- Helicobacter pylori as a cause of diseases classified under other headings
- K21
- Gastroesophageal reflux
- K25
- Stomach ulcer
- K26
- Duodenal ulcer