Instructions for Primafungin (Natamycin) vaginal suppositories 100 mg
English product фname Natamycin
Primafungin
Release Form
Rectal suppositories
Description Primafungin
Liquid rectal suppositories are a light yellow to yellow or cream coloured suppositories which are used in the treatment of respiratory problems and may be treated with an air rod or a funnel-shaped recess.
1 soupp.
natamitsin 100 mg
Auxiliary substances: patented form - Suppocyr AM® (semi-synthetic glycerides) for maximum uniform distribution of the active substance, Cetyl alcohol - 690 mg, sorbitan trioleate - 460 mg, polysorbate 80 - 460 mg, sodium hydrogen carbonate - 69 mg, adipic acid - 64 mg.
3 pcs. - packages of box-type contour (1) - cardboard packs.
3 pcs. - packages of box-type contour (2) - cardboard packs.
ATC codes
G01AA02 Natamycin
Clinical-pharmacological groups / Group affiliation
Antifungal drug for topical use in gynaecology
Active substance Natamycin
natamitsin
Pharmaco-therapeutic group Primafungin
Antifungal agent
Storage Conditions
Store the drug in a dry, light-proof place, inaccessible to children, at a temperature of 15° to 25°C.
Best before date Natamycin
The shelf life is two years. Do not use after the expiry date specified on the package.
Testimony Primafungin
fungal lesions of the vulva and vagina;
with a preventive purpose in the treatment of cytostatics, glucocorticoids or broad-spectrum antibiotics.
Method of use, course and dosage Primafungin
Intravaginally. In adults and girls (after the onset of sexual activity), one suppository is prescribed for three to six days.
The suppository is introduced into the vagina and in a prone position as deeply as possible, once a day at night. The product should not be cut into pieces as such a change in the drug's storage conditions may lead to a violation of the active substance's distribution.
Pharmacological effect Primafungin
Antifungal polyene antibiotic from the macrolide group, having a wide spectrum of action. It has a fungicidal effect. Natamycin binds cell membrane sterols, disrupting their integrity and function, leading to the death of microorganisms.
It is active against most pathogenic yeast-like fungi (especially Candida albicans), dermatophytes (Trichophyton, Microsporum, Epidermophyton), yeast (Torulopsis, Rhodotorula), other pathogenic fungi (Aspergillus, Penicillium, Fusarium, Cephalosporium), and some protozoa (trichomonad). Does not affect gram-positive and gram-negative bacteria.
Resistance to natamycin is not found in clinical practice.
- Nosology Primafungin (ICD codes)
- B37.3
- Candidiasis of the vulva and vagina
