Rhinostop (Xylometazoline) spray

Instructions for Rhinostop (Xylometazoline)

pharmachologic effect Rhinostop:

Decongestant agent

ATC: R.01.AB Sympathomimetics in combination with other medications (excepting corticosteroids)

Pharmacodynamics Rhinostop:

Xylometazoline - belongs to the group of local vasoconstrictor agents (decongestants) with alpha-adrenomimetic activity, causes narrowing of the blood vessels of the nasal mucosa, reduces hyperemia and edema of the mucous membrane, restores the patency of the nasal passages, facilitates nasal breathing and thereby reduces the symptoms of rhinitis. The effect of the drug usually occurs within a few minutes after its use and lasts up to 10 hours.

Dexpanthenol - a B vitamin - a derivative of pantothenic acid. Dexpanthenol is converted in the body into pantothenic acid, which is an integral part of coenzyme A, and is involved in acetylation processes, carbohydrate and fat metabolism, in the synthesis of acetylcholine, corticosteroids, porphyrins; stimulates the regeneration of the skin, mucous membranes, normalizes cell metabolism, accelerates mitosis and increases the strength of collagen fibers. It has a regenerating, metabolic and mild anti-inflammatory effect. Xylometazoline

Pharmacokinetics Rhinostop:

Xylometazoline hydrochloride, when applied topically, is practically not absorbed, plasma concentrations are so small that they cannot be determined by modern analytical methods.

Dexpanthenol, when applied topically, is rapidly absorbed by the skin and turns into pantothenic acid, binds to plasma proteins (mainly beta-globulin and albumin). Its concentration in blood is 0.5-1 mg / l, in blood serum - 100 μg / l. Pantothenic acid is not metabolized in the body (except for inclusion in Co-A), it is excreted unchanged.

Indications Rhinostop:

Acute respiratory diseases with symptoms of rhinitis
acute allergic rhinitis
vasomotor rhinitis
sinusitis
otitis media (as part of combination therapy to reduce swelling of the nasopharyngeal mucosa)
to facilitate rhinoscopy
to restore impaired nasal breathing after surgical interventions in the nasal cavity. Xylometazoline

Application during pregnancy and lactation Rhinostop:

The drug Xylometazoline should not be used during pregnancy.
The drug Xylometazoline is contraindicated during breastfeeding.
Consult a physician prior to use if you are pregnant or think you might be pregnant or planning to become pregnant.

Contraindications Rhinostop:

Hypersensitivity to the components of the drug, arterial hypertension, tachycardia, severe atherosclerosis, hyperthyroidism, glaucoma, atrophic rhinitis, dry rhinitis, porphyria, prostatic hyperplasia, surgical interventions on the meninges (in history), simultaneous use with monoamine oxidase inhibitors (MAO) antidepressants, pregnancy, breastfeeding, children under 6 years of age. Rhinostop
Carefully:
Diabetes mellitus, pheochromocytoma, diseases of the cardiovascular system (including coronary heart disease), hypersensitivity to the action of adrenergic drugs, accompanied by insomnia, dizziness, arrhythmia, tremor, increased blood pressure.

If you have one or more of the above diseases and conditions. then before you start taking it is necessary to consult a doctor.

Side effects Rhinostop:

The adverse events presented below are listed depending on the anatomophysiological classification and frequency of occurrence.

The frequency of occurrence is determined as follows: very often (with a frequency of more than 1/10), often (with a frequency of at least 1/100, but less than 1/10), infrequently (with a frequency of at least 1/1000, but less than 1/100) , rarely (with a frequency of at least 1/10000, but less than 1/1000), very rarely (with a frequency of less than 1/10000), unknown (the frequency is unknown based on the available data).
Nervous system disorders:
Very rare: anxiety, insomnia, headache, fatigue (drowsiness), hallucinations (mainly in children).
Cardiovascular system disorders:
Rarely: palpitations, tachycardia, increased blood pressure.
Very rare: arrhythmia.
Respiratory system disorders:
Very rare: swelling of the nasal mucosa, hypersecretion, nosebleeds.
Frequency not known: burning and dryness of the nasal mucosa, sneezing.
Musculoskeletal system disorders:
Very rare: seizures (especially in children).
Immune system disorders:
Very rare: allergic reactions (angioedema, skin rash, itching).
If any of the side effects indicated in the instructions are aggravated, or you notice any other side effects not listed in the instructions, inform your doctor.

Interaction Xylometazoline
With the simultaneous use of MAO inhibitors and tricyclic antidepressants, an increase in systemic action is possible.
If you are using any other medications (including over-the-counter) at the same time, consult your doctor before use.

How to take Rhinostop:

Intranasally. Rhinostop
For adults and children over 6 years old
When using a nasal spray, the bottle must be kept upright. Before use, you must clean the nasal passages.
During injection, you need to inhale easily through your nose. One injection into each nasal passage up to 3-4 times a day.
The duration of therapy is 5-7 days. Xylometazoline
Should not be used for more than 7 days. The duration of the use of the drug in children is established after consulting a doctor.
Reapplication is possible only after a break of several days.
If after 5 days of treatment there is no improvement or symptoms worsen, or new symptoms appear, you should consult your doctor. Use the drug only according to the indications, the method of administration and the doses indicated in the instructions. Rhinostop