Instructions for Skinoren
azelaic acid (micronized): 150 mg
Skinoren gel (azelaic acid)
Excipients: propylene glycol - 120 mg
polysorbate 80 - 15 mg
lecithin - 10 mg
polyacrylic acid - 10 mg
triglycerides - 10 mg
sodium hydroxide - 2 mg
disodium edetate - 1 mg
benzoic acid - 1 mg
purified water - 681 mg
Clinical and pharmacological groups / Group affiliation
Drug for the treatment of acne and rosacea
The drug with antiproliferative and antibacterial action
Active substance Skinoren:
azelaic acid micronized
Pharmaco-therapeutic group Skinoren:
Acne rash treatment
Storage conditions Skinoren:
The drug in the form of a gel should be stored out of the reach of children at a temperature not exceeding 25 ° C.
pharmachologic effect Skinoren:
A drug azelaic acid for the treatment of acne. Azelaic acid normalizes disturbed processes of keratinization in the follicles of the sebaceous glands, reduces the content of free fatty acids in the lipids of the skin and reduces its fat content. Shows antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis. The anti-inflammatory effect is also due to a decrease in neutrophil metabolism and a decrease in the production of free radical forms of oxygen. Azelaic acid has a dose- and time-dependent suppressive effect on the growth and viability of abnormal melanocytes.
- acne (acne vulgaris)
- incl. melasma
- chloasma (for cream)
- rosacea (for gel)
Method of application Skinoren (azelaic acid):
The dosage regimen and the duration of therapy are set individually. The drug is prescribed for adults and children over 12 years of age .
Before using the drug azelaic acid, the skin should be cleaned with water or a mild cosmetic cleansing agent, then dried.
The cream or gel is applied to the affected skin areas evenly with a thin layer 2 times / day (morning and evening) and rubbed lightly. The drug should be used in sufficient quantity, but not excessively (approximately 2.5 cm is sufficient for the entire surface of the face). The drug should be used regularly throughout the course of treatment, the duration of which depends on the clinical picture of the disease and the severity of symptoms. With acne (acne vulgaris), improvement is usually seen after 4 weeks. For best results, use of the drug should be continued for several months. Additional protection of the skin from UV radiation is not required during acne treatment.
For melasma, the drug is used in the form of a cream. The minimum duration of treatment is 3 months for the best results, you should regularly use the cream Skinoren ® . During the entire period of melasma therapy, it is imperative to use sunscreen (UVB and UVA) to prevent sun-induced exacerbation of the disease and / or re-pigmentation of the bleached areas.
To date, there is no information on overdose.
Drug interactions Skinoren:
Interaction Skinoren drug azelaic acid ® with other drugs have not yet been identified.
Application during pregnancy and lactation.
Application during pregnancy and lactation is possible after consulting a doctor, however, you should avoid applying it to the breast area before feeding.
Side effect Skinoren:
At the beginning of treatment, a small number of patients may experience local irritation, manifested in the form of hyperemia, peeling, erythema, burning, itching. In most cases, these symptoms are not very pronounced and go away on their own within a few days during the treatment process.
In very rare cases, allergic skin reactions (rash) are possible.
Contraindications for use Skinoren:
hypersensitivity to drug azelaic acid components.
special instructions Skinoren:
In cases of skin irritation, the amount of a single application of the gel or cream should be reduced or the frequency of application of the drug should be reduced to 1 time / day; if necessary, a short-term cancellation of the drug is possible (for several days).
Avoid getting the drug azelaic acid in the eyes and on the wound surfaces; in case of accidental contact, wash immediately with water.
Additional protection of the skin from UV radiation is not required during treatment with Skinoren.
Epidermal and mixed epidermal-dermal types of melasma respond well to Skinoren ® cream therapy.
Skinoren ® cream is not effective for dermal melasma . For differential diagnosis, it is recommended to use a Wood lamp.
5. Azelaic Acid