Spazgan (Fenpiverinium, Pitofenone, Metamizole)

Spazgan (Fenpiverinium, Pitofenone, Metamizole)

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Spazgan (Fenpiverinium, Pitofenone, Metamizole) a combined preparation, belongs to the group of aldegic and antispasmodic agents, has an analgesic, antipyretic, and weak anti-inflammatory effect
Active substance:Fenpiverinium, Pitofenone, Metamizole
Pharmacological group:Pain relievers
Country of origin:India
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Instructions for Spazgan (Fenpiverinium, Pitofenone, Metamizole)

English product name

Form of release
tab. 500 mg + 5 mg + 100 mcg: 20 or 100 pcs.

Description Spazgan:

Tablets 1 tab.
metamizole sodium 500 mg
pitophenone hydrochloride 5 mg
fenpiverininia bromide 100 mcg

ATC codes
A03DA02 Pitophenone in combination with analgesics

Clinical and pharmacological groups / Group affiliation

Active ingredient
metamizole sodium
pitophenone hydrochloride
fenpiverininia bromide

Pharmaco-therapeutic group

Analgesic non-narcotic agent (analgesic non-narcotic + antispasmodic)

Testimony Spazgan:

  • Pain syndrome (weakly or moderately pronounced) with spasms of smooth muscles of internal organs:
  • renal colic,
  • spasm of the ureter and bladder;
  • biliary colic;
  • biliary dyskinesia; postcholeciestectomy syndrome;
  • intestinal colic;
  • chronic colitis;
  • algodismenorrhea;
  • diseases of the pelvic organs.
  • For short-term treatment of arthralgia; myalgia; neuralgia, sciatica.
  • As an auxiliary drug Fenpiverinium for pain syndrome after surgical interventions and diagnostic procedures.

Method of administration, course and dosage:


Adults and adolescents over 15 years: 1-2 tab. 2-3 times / day, without chewing, washed down with a small amount of liquid.

Children aged 12-14 years : single dose of 1 tab., the maximum daily dose of 6 tab. (1.5 tab. 4 times / day), children aged 8-11 years, 0.5 tab., the maximum daily dose of 4 tab. (1 tab. 4 times / day), children aged 5-7 years, 0.5 tab., The maximum daily dose of 2 tab. (0.5 tab. 4 times / day).

Parenterally (in / in, in / m)
Adults and adolescents over 15 years of age with acute severe colic enter in / in slowly (1 ml for 1 minute) to 2 ml; If necessary, re-enter through 6-8 hours In / m-2-5 ml solution 2-3 times / day. The maximum daily dose should not exceed 10 ml (which corresponds to 5 g of metamizole sodium).

The duration of treatment is determined depending on the clinical symptoms and etiopathogenesis of the disease, but should not exceed 5 days.

Calculation of the dose for children with the on / in and / m introduction :
three - ELEVEN months (5-8 kg) - only in / m - 0.1-0.2 ml;
one to two years (9-15 kg) - in / in - 0.1-0.2 ml, in / m - 0.2-0.3 ml;
Three - four years (16-23 kg) - in / in - 0.2-0.3, in / m - 0.3-0.4 ml;
5-7 years (24-30 kg) - in / in - 0.3-0.4 ml, in / m - 0.4-0.5 ml;
8-12 years (31-45 kg) - in / in - 0.5-0.6 ml, in / m - 0.6-0.7 ml;
12-15 years - in / in and / m - 0.8-1 ml.

Before the introduction of the injection solution, it should be warmed in the hand.

Use in violation of renal function
Contraindicated use of the drug with severe renal failure.

FROM caution should be prescribed the drug in renal failure.

Use in violation of liver function
Contraindicated use of the drug with severe liver failure.

FROM caution should be prescribed the drug with liver failure.

Use in children
Contraindicated in / in the introduction of the drug Fenpiverinium in childhood up to 3 months or with a body weight of less than 5 kg.

Contraindicated use of the drug Fenpiverinium in the form of tablets in children under 5 years.

  • Nosology Spazgan (ICD codes)
  • K52.9
  • Non-infectious gastroenteritis and unspecified colitis
  • K80
  • Cholelithiasis [cholelithiasis] (incl. hepatic colic)
  • K82.8
  • Other specified diseases of the gallbladder and gallbladder duct (including dyskinesia)
  • K91.5
  • Postcholecystectomy syndrome
  • M25.5
  • Joint pain
  • M54.1
  • Radiculopathy
  • M54.3
  • Sciatica
  • M54.4
  • Lumbago with sciatica
  • M79.1
  • Myalgia
  • M79.2
  • Neuralgia and neuritis unspecified
  • N23
  • Renal colic unspecified
  • N94.4
  • Primary dysmenorrhea
  • N94.5
  • Secondary dysmenorrhea
  • R10.4
  • Other and unspecified abdominal pain (colic)
  • R52.0
  • Pang
  • R52.2
  • Other persistent pain (chronic)

Drugs Spazgan:

Combined analgesic and antispasmodic agent. The combination of the components of the drug Fenpiverinium leads to mutual strengthening of their pharmacological action.

Metamizole sodium - a derivative of pyrazolone, has analgesic, antipyretic and weak anti-inflammatory effect, the mechanism of which is associated with inhibition of the synthesis of prostaglandins.

Pitophenone hydrochloride has a direct myotropic effect on the smooth muscles of the internal organs and causes its relaxation (papaverine-like effect).
Fenpiverinia bromide has an m-holinoblokruyuschim effect and has an additional myotropic effect on smooth muscles.

Active substance
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